Zinforo

by Pfizer

Active ingredient: Ceftaroline fosamil

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About Ceftaroline Fosamil

Cephalosporin

Uses

Complicated SSTI, Community-acquired pneumonia.

How to take it

Adults: By IV infusion: 600mg over 60 minutes every 12 hours. Continue for 5-7 days in pneumonia and for 5-14 days in SSTI. Geriatrics: Same as adults. Children: Recommended durations of treatment are 5-14 days for cSSTI and 5-7 days for CAP. 12-18 yrs: Body wt: =33 kg: 600 mg over 60 mins every 12 hrs. Body wt <33kg: 12 mg/kg to a max of 400 mg over 60 mins every 8 hrs. =2yrs-<12 yrs: 12 mg/kg to a max of 400 mg over 60 mins every 8 hrs. Infants =2 mths-<2yrs: 8 mg/kg over 60 mins every 8 hrs. Neonates from birth-<2 mths: 6 mg/kg over 60 mins every 8 hrs. Administered by IV infusion over 1 hour. Reconstitution: The contents of ceftaroline fosamil vial should be reconstituted with 20 mL of…

Side effects

Positive coombs test, rash, pruritus, GI upset, raised LFTs, fever, headache, dizziness, phlebitis, infusion site reactions, hypersensitivity reactions, pseudomembranous colitis, haemolytic anaemia.

Pregnancy and breastfeeding

Pregnancy: Contraindicated in pregnancy. Lactation: Contraindicated or not recommended. Contraindications: Hypersensitivity to the cephalosporin class of antibacterials. Immediate and severe hypersensitivity (e.g. anaphylactic reaction) to any other type of beta-lactam antibacterial agent (e.g. penicillins or carbapenems). Precautions: Non-severe hypersensitivity to other B-lactams, renal impairment (CrCl < 50ml/mins), history of seizures, pork risk class V and/or pneumonia requiring ventilation at presentation, pneumonia due to MRSA or requiring intensive care, immunocompromised, severe sepsis or septic shock, pneumonia, severe underlying lung disease.

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Compiled by Healify Pharmacy from published drug references. How we compile it →

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