Ibuprofen

by Unexo

Active ingredient: Ibuprofen

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About Ibuprofen

Anti-rheumatic, Systemic

Uses

Rheumatoid arthritis, juvenile rheumatoid arthritis (JRA), ankylosing spondylitis, osteoarthrosis, seronegative arthropathies, peri-articular disorders, soft tissue injuries. Mild to moderate pain. Fever.

How to take it

ORAL: Adults: 1200-1800 mg daily in divided doses. Max 2400 mg daily. Dysmenorrhoea: 400 mg every 4 hr if needed. Inflammatory Disease: 400-800 mg every 6-8 hr. Max: 3.2 gm/day. Pain/fever: 200-400 mg every 4-6 hr. Max: 1.2 gm/day. Children: Not recommended for children under 3 mth or body-weight under 5 kg. Mild to moderate pain, pain and inflammation of soft-tissue injuries, pyrexia with discomfort: 3-6 mth, body-weight > 5 kg: 50 mg 3 times daily, max 30 mg/kg daily in 3-4 divided doses; 6 mth-1 yr, 50 mg 3-4 times daily, max 30 mg/kg daily in 3-4 divided doses; 1-4 yr, 100 mg 3 times daily, max 30 mg/kg daily in 3-4 divided doses; 4-7 yr, 150 mg 3 times daily, max 30 mg/kg daily in 3-4…

Side effects

Gl upset or bleeding, rash, rarely thrombocytopenia, rarely aseptic meningitis, neutropenia, periventricular leukomalacia, bronchopulmonary dysplasia, necrotising enterocolitis, intestinal perforation, oliguria, fluid retention, haematuria. Raised creatinine and hyponatraemia.

Pregnancy and breastfeeding

Pregnancy: Risk cannot be ruled out. Lactation: Caution advised or effect undetermined. Contraindications: Severe renal impairment. Life threatening infection, active bleeding, thrombocytopenia or coagulation defects, necrotising enterocolitis, marked hyperbilirubinaemia, ductal-dependent congenital heart disease. Precautions: Monitor renal and GI function. ECG must be carried out before administration to exclude pulmonary hypertension and ductal-dependent congenital heart disease. If hypoxaemia occurs, monitor pulmonary pressure. Infection.

Advice

Take immediately after meals. Take tablets with a glass of water. Do not lie down for 15-30 minutes after taking medication. Do not take medication for more than 3 days for fever and more than 10 days for pain without consulting prescriber. Discontinue taking medication and inform prescriber if there is unrelieved nausea or vomiting, constant stomach pain or cramps, indigestion, ringing in ears, changes in hearing, unusual bruising or bleeding, difficulty in breathing, blood in urine/mouth/stool, unusual swelling of extremities, skin rash, itching, blisters, chest pain, palpitations, difficulty in speaking. Avoid alcohol, increased amount of vitamin C, salicylate containing foods (curry…

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Interactions with Ibuprofen

Anticoagulants, thiazide diuretics, quinolones, aminoglycosides, nitric oxide, antihypertensives, digoxin, lithium, methotrexate, cyclosporin, mifepristone, other NSAIDs, corticosteroids.

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Compiled by Healify Pharmacy from published drug references. How we compile it →

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