Grandaxin

by Medimpex

Active ingredient: Tofisopam

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About Tofisopam

Tranquilizer, Sedative/Hypnotic

Uses

Anxiety.

How to take it

Adults: 50 mg three times daily; up to 300 mg daily. Children: Not recommended.

Side effects

Drowsiness and light headedness, which may continue into the following day. Muscle weakness, ataxia, confusion, vertigo, GI upset, hypotension, visual disturbance, rash, impaired alertness and dexterity, headache, urinary pretension, changes in libido. Rarely blood disorder, jaundice, respiratory depression, abnormal psychological reactions. Paradoxical reactions, anterograde amnesia. Dependence.

Pregnancy and breastfeeding

Pregnancy: Contraindicated in pregnancy. Lactation: Caution advised or effect undetermined. Contraindications: Acute pulmonary insufficiency, respiratory depression, sleep apnoea, phobic or obsessional state, chronic psychosis, unstable Myasthaenia gravis. Severe hepatic impairment. As monotherapy to treat depression or anxiety associated with depression. Precautions: Chronic pulmonary insufficiency, Myasthaenia gravis, renal impairment, mild to moderate hepatic impairment, history of drugs or alcohol abuse, personality disorders, Elderly, avoid long-term use. Withdraw gradually.

Advice

Take last dose before 5 pm to avoid sleep disturbances.

Full information on Tofisopam →

Interactions with Tofisopam

Alcohol, CNS depressants, anticonvulsants, CYP3A4 inhibitors or inducers (e.g. cimetidine, rifampicin).

Tell your pharmacist or doctor about every medicine you take, including herbal products.

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More from Medimpex

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.