Embol
by Mcolson
Active ingredient: Ranolazine
Packs
- Tab · 500 mg · 14's (105706)
In stock at Healify — same active ingredient
Always confirm a substitution with your pharmacist.
About Ranolazine
Cardiac Therapy
Uses
Adjunctive therapy in the treatment of stable angina in patients inadequately controlled on 1st line antianginal therapy.
How to take it
Adults: Initially 375 mg twice daily, increasing after 2-4 wk to 500 mg twice daily. Max, 750 mg twice daily according to response. Children: Not recommended.
Side effects
Dizziness, headache, GI upset, asthaenia.
Pregnancy and breastfeeding
Pregnancy: Contraindicated in pregnancy. Lactation: Contraindicated or not recommended. Contraindications: Severe renal impairment ( CrCl <30mL/min), moderate or severe hepatic impairment. Precautions: Moderate to severe CHF, CYP2D6 poor metabolisers, QT interval prolongation, elderly, body wt < 60 kg, mild to moderate hepatic & renal impairment.
Advice
Take with or without meals. Swallow tablets whole, do not chew, crush or break them. Reduce intake of grapefruit and grapefruit juice during treatment.
Full information on Ranolazine →
Interactions with Ranolazine
CYP3A4 inhibitors & inducers, CYP2D6 inhibitors (e.g., paroxetine) or substrates (e.g., TCADs, antipsychotics), calcium channel blockers, anti-arrhythmics, anticonvulsants, macrolides, digoxin, drugs that prolong QT intervals. P-gp inhibitors (e.g., verapamil, cyclosporin) or substrates, CYP2B6 substrates (bupropion, efavirenz, cyclophosphamide), digoxin.
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Compiled by Healify Pharmacy from published drug references. How we compile it →
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