Rancard

by Searle

Active ingredient: Ranolazine

PKR 500

Available at Healify

Rancard-XR Tablets 500mg (1 Box = 2 Strips) (1 Strip = 7 Tablets) · Box · PKR 500 · In stock

Manufactured by SEARLE PAKISTAN (PVT) LTD.

Other packs (not sold online by Healify)

Tab · 1000 mg · 14's

About Ranolazine

Cardiac Therapy

Uses

Adjunctive therapy in the treatment of stable angina in patients inadequately controlled on 1st line antianginal therapy.

How to take it

Adults: Initially 375 mg twice daily, increasing after 2-4 wk to 500 mg twice daily. Max, 750 mg twice daily according to response. Children: Not recommended.

Side effects

Dizziness, headache, GI upset, asthaenia.

Pregnancy and breastfeeding

Pregnancy: Contraindicated in pregnancy. Lactation: Contraindicated or not recommended. Contraindications: Severe renal impairment ( CrCl <30mL/min), moderate or severe hepatic impairment. Precautions: Moderate to severe CHF, CYP2D6 poor metabolisers, QT interval prolongation, elderly, body wt < 60 kg, mild to moderate hepatic & renal impairment.

Advice

Take with or without meals. Swallow tablets whole, do not chew, crush or break them. Reduce intake of grapefruit and grapefruit juice during treatment.

Full information on Ranolazine →

Interactions with Ranolazine

CYP3A4 inhibitors & inducers, CYP2D6 inhibitors (e.g., paroxetine) or substrates (e.g., TCADs, antipsychotics), calcium channel blockers, anti-arrhythmics, anticonvulsants, macrolides, digoxin, drugs that prolong QT intervals. P-gp inhibitors (e.g., verapamil, cyclosporin) or substrates, CYP2B6 substrates (bupropion, efavirenz, cyclophosphamide), digoxin.

Tell your pharmacist or doctor about every medicine you take, including herbal products.