Cyclidine

by Pharmedic

Active ingredient: Procyclidine

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About Procyclidine

Antiparkinsonism Preps

Uses

Parkinsonism, drug-induced extra-pyramidal symptoms (but not tardive dyskinesia).

How to take it

ORAL: Adults: Initially 2.5 mg three times daily after meals increasing at intervals of 2 or 3 days by 2.5-5 mg daily; usual max 30 mg daily. INJECTION: Acute dystonia: Adults: BY IM or IV inj, 5-10 mg (occasionally more than 10 mg), usually effective in 5-10 min but may need 30 min for relief. Children: Not recommended.

Side effects

Mental confusion in high doses. Blurred vision, dry mouth, constipation, urinary retention.

Pregnancy and breastfeeding

Pregnancy: Risk cannot be ruled out. Lactation: Contraindicated or not recommended. Contraindications: Gl obstruction, urinary obstruction. Closed angle glaucoma. Precautions: Elderly. Prostatic hypertrophy, renal or hepatic impairment, tardive dyskinesia, psychiatric disorders, predisposition to glaucoma or GI obstruction. Cardiac disorders. Withdraw slowly.

Advice

Take after meals. Take at the same time each day. Contact prescriber if there is difficulty in breathing, unrelieved constipation, chest pain, palpitations, painful or difficult urination, loss of memory, nervousness, hallucinations, skin rash, increased muscle spasm, rigidity or if there is worsening of condition. Avoid alcohol during therapy. Do not take prescription medications, OTC sedatives or CNS depressants without consulting prescriber. Limit exercise activity, take sufficient amount of fluids to prevent heatstroke in hot weather. For nasal congestion or dry skin, consult prescriber for relief.

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Interactions with Procyclidine

Phenothiazines, antihistamines and antidepressants. MAOIs, TCADs, amantadine, memantine, disopyramide, nefopam, ketoconazole, levodopa, cholinergic agents, domperidone, metoclopramide, paroxetine, antipsychotics.

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Compiled by Healify Pharmacy from published drug references. How we compile it →

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