Afanix

by Himmel

Active ingredient: Afatinib

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About Afatinib

Cytostatic

Uses

It is indicated as monotherapy for the treatment of patients with advanced or metastatic non-squamous non-small cell carcinoma of the lung, either as first line therapy or after failure of cytotoxic chemotherapy.

How to take it

Adults: 40 mg once daily. Renal impairment: 30 mg once daily in patients with severe renal impairment. Dose may be adjusted as per requirement. Tablet should be taken at least 1 hour before or 2 hours after a meal. Children: Not recommended.

Side effects

Diarrhoea, rash, stomatitis, paronychia, dry skin, nose bleed, decreased appetite, nausea, vomiting, pruritus, keratitis, bullous and exfoliative Skin disorders, interstitial lung disease and hepatic toxicity.

Pregnancy and breastfeeding

Pregnancy: Contraindicated in pregnancy. Lactation: Contraindicated or not recommended.

Full information on Afatinib →

Interactions with Afatinib

Toritonavir, cyclosporine, ketoconazole, itraconazole, erythromycin, verapamil, quinidine, tacrolimus, nelfinavir, saquinavir, amiodarone, rifampicin, carbamazepine, phenytoin, phenobarbital and St. John's Wort.

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More from Himmel

Compiled by Healify Pharmacy from published drug references. How we compile it →

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