Caspo PMS

by Himmel

Active ingredient: Caspofungin

Packs

About Caspofungin

Antifungal, Systemic

Uses

Treatment of invasive candidiasis. Treatment of invasive aspergillosis in patients refractory to or intolerant of amphotericin and/or itraconazole. Empirical therapy for presumed fungal infections in febrile neutropenic patients.

How to take it

Adults: IV Inf: Under 80 kg: Initially 70 mg on Day 1, then 50 mg daily. Over 80 kg: 70 mg daily. Continue treatment of invasive candidiasis for 14 days after last positive culture and of invasive aspergillosis for 7 days after resolution of symptoms. Empirical therapy: Continue upto 72 hr after resolution of neutropenia. Fungal infection: Treat for minimum 14 days, continue treatment for atleast 7 days after both neutropenia and clinical symptoms resolve. Children: IV Inf: Under 1 yr: see literature. 1- 17 yr: Initially 70 mg /m2 on Day 1, then 50 mg/m2 daily increasing to 70 mg/m2 daily if required. Max 70 mg daily. Duration of treatment: as for Adult. Adults & Children: Reconstitute and…

Side effects

Inj site reactions, headache, dyspnoea, GI upset, rash, fever, pruritus, chills, arthralgia, raised liver enzymes, decreased haemoglobin and haematocrit, hypokalaemia, hypoalbuminaemia.

Pregnancy and breastfeeding

Pregnancy: Risk cannot be ruled out. Lactation: Contraindicated or not recommended. Contraindications: Hepatic impairment in children, severe hepatic impairment in adults. Precautions: Moderate hepatic impairment in adults.

Advice

This medication is administered by infusion only. Contact prescriber if there is burning/pain/swelling at infusion site or if there is difficulty in swallowing or breathing, back pain, chest tightness, hives, rash, swelling of mouth/lips, nausea, vomiting, abdominal pain, diarrhoea.

Full information on Caspofungin →

Interactions with Caspofungin

Cyclosporin, tacrolimus, rifampicin, efavirenz, nevirapine, dexamethasone, phenytoin, carbamazepine.

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Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.