C-Zol

by Genesis

Active ingredients: Cefazolin, Cephazolin

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About Cephazolin

Cephalosporin

Uses

Septicaemia; endocarditis; UTI, respiratory tract, skin and soft tissue infections. Cholecystitis.

How to take it

Adults: 500 mg-1 gm IM or IV 6-8 hourly. Children: Under 1 mth, not recommended; others, 25-50 mg/kg daily in three or four divided doses by IM or IV inj. Prophylaxis against bacterial endocarditis: Adults: 1 gm 30 min before procedure. Children: 25 mg/kg 30 min before procedure; max dose 1 gm. Bone and joint infections: Adults: IM/IV: 500-1000 mg every 6-8 hourly. Children: 25-50 mg/kg/day divided every 6-8 hourly doses. Max: 100 mg/kg/day. Septicaemia: IV: Adults: 1-1.5 gm every 6 hourly. Children: 100 mg/kg/day divided every 6-8 hourly doses. Cholecystitis, mild-to-moderate: Adults: 1-2 gm IV every 8 hrs for 4-7 days (provided source controlled). IM: Inject deep IM into large muscle…

Side effects

Pain at inj site, hypersensitivity reactions. Gl disturbances, convulsions, eosinophilia, neutropenia, leucopenia, rise in liver enzymes and blood urea. Positive Coomb's test.

Pregnancy and breastfeeding

Pregnancy: No evidence of risk in humans. Lactation: Caution advised or effect undetermined. Precautions: Hypersensitivity to beta-lactam antibiotics. In beta-haemolytic infections, continue therapy for at least ten days. Impaired renal function.

Advice

This medication is to be administered by injection or infusion only. Contact prescriber if there is burning/swelling/redness/pain at injection or infusion site or if there is rash, hives, itching, difficulty in breathing or swallowing, chest pain, severe unrelieved diarrhoea, vaginal drainage or itching, mouth sores, blood/pus/mucus in stool or urine, easy bruising or bleeding, unusual chills or fever. Watery or bloody stools can occur 2 or more months after therapy and can be serious, requiring immediate treatment. Complete full course of therapy even if you feel better. Take sufficient amount of fluids (2-3 litres per day) to maintain hydration, unless restricted by the prescriber.

Full information on Cephazolin →

Interactions with Cephazolin

Loop diuretics, probenecid, aminoglycosides.

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Compiled by Healify Pharmacy from published drug references. How we compile it →

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