Bromid

by Shrooq

Active ingredient: Rocuronium bromide

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About Rocuronium

Muscle Relaxant

Uses

Adjunct to general anaesthesia to facilitate tracheal intubation during routine and rapid sequence induction and to provide muscle relaxation for procedures.

How to take it

Adults: Intubation: By IV injection, initially 600 mcg/kg, maintenance by IV inj, 150 mcg/kg (Elderly: 75-100 mcg/kg) or maintenance by IV infusion, 300-600 mcg/kg/hr (Elderly: up to 400 mcg/kg/hr) adjusted according to response. Intensive care: By IV inj, initially 600 mcg/kg (optional), maintenance by IV infusion, 300-400 mcg/kg/hr for first hr, then adjusted according to response. Children: Not licensed for use in children for assisted ventilation in intensive care. To avoid excessive dosage in obese children, dose should be calculated on the basis of ideal weight. Neuromuscular blockade (intermediate duration) during surgery: Neonate, initially by IV injection 600 mcg/kg, then either by…

Side effects

High dosage produce mild vagolytic activity. Rash; injection site reactions.

Pregnancy and breastfeeding

Pregnancy: Risk cannot be ruled out. Lactation: Caution advised or effect undetermined. Precautions: Prior anaphylactic reactions; neuromuscular disease; acid-base, electrolyte imbalance; dehydration; hypothermia; obesity; cardiovascular disease; oedema; renal, hepatic, pulmonary impairment; elderly, infants (1-12 months).

Advice

Continuous monitoring is required during and after administration. After muscle tone becomes normal, do not change position and rise up without help. Contact prescriber if there is difficulty in breathing, muscle tremors, fast heartbeat, skin rash, hives.

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Compiled by Healify Pharmacy from published drug references. How we compile it →

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