Tofacit

by Kaizen

Active ingredient: Tofacitinib

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About Tofacitinib

Anti-rheumatic, Systemic

Uses

Rheumatoid arthritis.

How to take it

Adults: 5 mg twice daily. Children: Not recommended.

Side effects

Hypertension, headache, diarrhoea, UTI, increase ALT, increase creatinine, upper RTI, nasopharyngitis, serious infection, abdominal pain, anaemia, dehydration, drug induce liver injury, dyspepsia, dyspnoea, erythema, gastritis, hepatic steatosis, lymphocytopenia, musculoskeletal pain, neutropenia, peripheral edema, pruritus, pyrexia, rash, sinus congestion, tendonitis, tuberculosis, vomiting.

Pregnancy and breastfeeding

Pregnancy: Risk cannot be ruled out. Lactation: Contraindicated or not recommended. Contraindications: Severe hepatic impairment, live vaccination, tuberculosis, serious infections, lymphoma. Precautions: Patients who have been exposed to tuberculosis, with history of serious or opportunistic infection, patients who live in or travel to/from areas of endemic mycoses (blastomycosis, coccidioidomycosis, histoplasmosis). Elderly patients. Patients at increased risk for gastrointestinal perforation (e.g. history of diverticulitis).

Advice

Take with or without meals. Contact prescriber if there is severe tiredness, yellowing of skin or eyes, loss of appetite, fever, chills, vomiting, dark coloured stool, abdominal upset, muscle pain, dark urine, skin rash.

Full information on Tofacitinib →

Interactions with Tofacitinib

BCG, CYP3A4 inducers, natalizumab, tacrolimus, leflunomide, fluconazole, denosumab, dasatinib, ivacaftor, sitaxsentan, mifepristone, roflumilast, pimecrolimus.

Tell your pharmacist or doctor about every medicine you take, including herbal products.

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Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.