Tigelin

by Global/Vision

Active ingredient: Tigecycline

PKR 3,200

Available at Healify

Tigelin Iv Injection 50mg (1 Box = 1 Injection) · pc · PKR 3,200 · In stock

Manufactured by GLOBAL PHARMACEUTICALS.

About Tigecycline

Tetracycline

Uses

Complicated intra-abdominal infections, skin and soft tissue infections.

How to take it

Adults: By IV infusion, initially 100 mg then 50 mg every 12 hr for 5-14 days. Children: Not recommended. Administered by IV infusion over 30 to 60 min after dilution of the reconstituted solution in 100 mL of Dextrose 5% or NaCl 0.9 %. Reconstitution: Reconstitute the vials with 5.3 mL of NaCl 0.9% or D5W. The concentration should not exceed 1 mg/mL. The solution should be yellow to orange. Compatibility: Dextrose 5%, NaCl 0.9%. Stability: Reconstituted vial at room temperature for upto 6 hours with an additional 18 hours after dilution in the infusion solution or 48 hours in refrigerator.

Side effects

Gl disturbances, anorexia, dizziness, phlebitis, rash, headache, abscess, infections, raised ALT, AST, BUN, amylase, prolonged APTT/PT, raised INR, pruritus, inj site reactions, impaired healing, hypoglycaemia, hypoproteinaemia, increased LFTs, hepatic failure, pseudomembranous colitis and anaphylaxis.

Pregnancy and breastfeeding

Pregnancy: Contraindicated in pregnancy. Lactation: Contraindicated or not recommended. Contraindications: Foot infections in diabetic patients. Precautions: Severe hepatic impairment, cholestasis, monitor for signs of acute pancreatitis, consider withdrawal if suspected. Tetracycline hypersensitivity. Severe underlying disease or concurrent bacteremia. Monitor for superinfection. Children: Monitor LFTs, coagulation, haematology, amylase and lipase.

Advice

Contact prescriber if there is itching, rash, severe diarrhoea, watery or bloody stools, pain at infusion site. Watery or bloody stools can occur 2 or more months after therapy and can be serious, requiring immediate treatment.

Full information on Tigecycline →

Interactions with Tigecycline

Anticoagulants, P-gp inhibitors or inducers.

Tell your pharmacist or doctor about every medicine you take, including herbal products.