Streptomycin

by PDH Pharma

Active ingredient: Streptomycin

Packs

About Streptomycin

Antituberculosis Preps

Uses

Treatment of tuberculosis only in conjunction with other anti-tuberculous drugs.

How to take it

Adults: IM: 15-30 mg/kg/day when used as a daily therapy. Max 1 gm. Children: IM: 20-40 mg/kg/day when used as a daily therapy. Max 1 gm/day. Reconstitute with 4.2, 3.2, or 1.8 mL of SWFI to yield solutions containing 200, 250, or 400 mg/mL, respectively. Administered by deep IM injection well within the body of a relatively large muscle. IV route is not recommended. Stability: Reconstituted solutions are stable for 1 week at room temperature and protect from light.

Side effects

Nephrotoxicity and ototoxicity.

Pregnancy and breastfeeding

Pregnancy: Positive evidence of risk: Use only when no safer alternative exists for a serious problem. Lactation: Caution advised or effect undetermined. Contraindications: Hypersensitivity. Precautions: Use with caution in patients with pre-existing vertigo, tinnitus, hearing impairment.

Advice

Therapy may last several months. Contact prescriber if there is vertigo, change in hearing, feeling of fullness in ears, loss of hearing, numbness, pain, tremors, weakness in muscles, change in gait, back pain, change in urinary pattern, chest pain, difficulty in breathing. Complete full course of therapy even if you feel better. Take sufficient amount of fluids (2-3 litres per day) to maintain hydration, unless restricted by the prescriber.

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Interactions with Streptomycin

Depolarizing and non-depolarizing neuromuscular blocking agents, amphotericin, loop diuretics.

Tell your pharmacist or doctor about every medicine you take, including herbal products.

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More from PDH Pharma

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.