Simulect

by Novartis/Nouveaux

Active ingredient: Basiliximab

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About Basiliximab

Immunomodulator

Uses

Prophylaxis of renal allograft rejection. As an adjunct to Neoral and corticosteroids for the prophylaxis of acute organ rejection in de novo allogeneic renal transplantation.

How to take it

See literature. Two doses, the first within 2 hr before transplantation surgery, the sec 4 days after transplantation. Adults: 20 mg basiliximab per dose. Children: (aged 2 yr or older) weighing less than 40 kg: 10 mg per dose. Children (aged 2 yr or older) weighing 40 kg or more, same as adult dose. For central or peripheral IV administration only. Reconstituted solution should be given either as a bolus injection or diluted and administered as an IV infusion over 20-30 min. Reconstitution: To prepare the reconstituted solution, add 2.5 mL (10 mg vial) or 5 mL (20 mg vial) of SWFI, using aseptic technique, to the vial containing the basiliximab powder. Shake the vial gently to dissolve the…

Side effects

Rare case of hypersensitivity/anaphylactoid type reaction such as rash, urticaria, sneezing, wheezing, bronchospasm, pulmonary oedema, cardiac failure, respiratory failure and capillary leak syndrome have been reported.

Pregnancy and breastfeeding

Contraindications: Pregnancy. Women receiving Simulect should not breast-feed for 8 weeks after the second dose.

Full information on Basiliximab →

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Compiled by Healify Pharmacy from published drug references. How we compile it →

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