Selgin

by Valor/Al-Hameed

Active ingredient: Selegiline

Packs

About Selegiline

Antiparkinsonism Preps

Uses

Parkinsonism in conjunction with levodopa therapy particularly in patients on levodopa who develop on-off symptoms/ other dyskinesias.

How to take it

Adults: 2 tab as a single dose in the morning or in divided doses at breakfast and lunch. Children: Not recommended.

Side effects

Postural hypotension, BP changes, involuntary movements (reduce levodopa dose). Nausea, confusion or psychosis, bradycardia, chest pain, GI upset, headache, tremor, dizziness, depression, hallucinations, agitation, dry mouth, sore throat, nasal congestion, difficulty in micturition, skin reactions, joint or muscle pain, muscle cramps, increased dyskinesias, insomnia, abnormal dreams, transient increase in liver enzymes, hyperhidrosis, falls.

Pregnancy and breastfeeding

Pregnancy: Risk cannot be ruled out. Lactation: Contraindicated or not recommended. Contraindications: Active duodenal or gastric ulcer. Precautions: Severe renal or hepatic impairment, avoid abrupt withdrawal, uncontrolled hypertension, arrhythmias, psychosis, acute porphyria, history of peptic ulcer. Surgery.

Advice

Take with meals. Take at the same time each day. Avoid taking in late afternoon and evening. Take disintegrating tablets before breakfast without any liquid. Wash hands well after application of transdermal patch and dispose off removed patch immediately. Rotate sites for application of patch. If a patch falls off, apply a new patch to a new site and to return to previous schedule. Contact prescriber if there is acute headache, unrelieved vomiting or constipation, loss of memory, chest pain, palpitations, irregular heartbeat, nervousness, seizures, hallucinations, skin rash, increased muscle spasm, rigidity, involuntary movements, painful or difficult urination, dry mouth that lasts more…

Full information on Selegiline →

Interactions with Selegiline

MAOIs, alcohol, antidepressants, opioids, dopamine, sympathomimetics, serotonin agonists, CNS stimulants or depressants, oral contraceptives, HRT, amantadine, anticholinergics, digoxin, anticoagulants, drugs that affect BP.

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Compiled by Healify Pharmacy from published drug references. How we compile it →

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