Axinib

by Amgomed

Active ingredient: Axitinib

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About Axitinib

Cytostatic

Uses

Advanced renal cell carcinoma (RCC) after failure of one prior systemic therapy.

How to take it

The starting dose is 5 mg orally twice daily. Dose adjustments can be made based on individual safety and tolerability.

Side effects

The most common (=20%) adverse reactions are diarrhoea, hypertension, fatigue, decreased appetite, nausea, dysphonia, palmar-plantar erythrodysesthesia (hand-foot) syndrome, weight decreased, vomiting, asthaenia and constipation.

Pregnancy and breastfeeding

Precautions: Hypertension, arterial and venous thrombotic, Hemorrhagic events.

Advice

Take with or without meals. Swallow tablet whole with water. Contact prescriber if there is severe diarrhoea, nosebleed, bleeding from gums, headache, muscle ache, cough, sore throat, difficulty in urination, cold, shivering. Take plenty of fluids during therapy. Avoid grapefruit and grapefruit juice during therapy. Avoid immunisation with live vaccines during treatment and for 6 months after completion of treatment.

Full information on Axitinib →

Interactions with Axitinib

Dexamethasone, bosentan, modafinil, St. John's Wort (Hypericum perforatum), or medicine for asthma, tuberculosis, seizures, bacterial infections, fungal infections, depression, or HIV/AIDS.

Tell your pharmacist or doctor about every medicine you take, including herbal products.

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More from Amgomed

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.