Pyrrolite

by Elite

Active ingredients: Glycopyrrolate, Neostigmine

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In stock at Healify — same active ingredient

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About Glycopyrrolate

Other CNS Drugs

Uses

Inhibit salivation and excessive secretions of the respiratory tract pre-operatively; reversal of neuromuscular blockade; control of upper airway secretions; adjunct in treatment of peptic ulcer.

How to take it

Adults: INJECTION: Control of secretions: Intra-operative: IV: 0.1 mg repeated as needed at 2-3 mins intervals. Preoperative: IM: 4.4 mcg/kg 30-60 min before procedure. Reverse neuromuscular blockade: IV: 0.2 mg for each 1 mg of neostigmine or 5 mg of pyridostigmine administered or 5-15 mcg/kg glycopyrrolate with 25-70 mcg/kg of neostigmine or 0.1-0.3 mg/kg of pyridostigmine (agents usually administered simultaneously, but glycopyrrolate may be administered first if bradycardia is present). Peptic ulcer: IM/IV: 0.1-0.2 mg 3-4 times/day. Adults: ORAL: Peptic ulcer: 1-2 mg 2-3 times daily. Children: INJECTION: Premedication at induction: IV or IM injection: Neonate, 5 mcg/kg; 1 mth-12 yr, 4-8…

Side effects

Dry skin. Constipation, dry throat, dry mouth. Irritation at injection site. Dry nose. Diaphoresis (decreased).

Pregnancy and breastfeeding

Pregnancy: No evidence of risk in humans. Lactation: Caution advised or effect undetermined. Contraindications: Hypersensitivity to glycopyrrolate or any component of the formulation; ulcerative colitis; narrow-angle glaucoma; acute haemorrhage; tachycardia; obstructive uropathy; paralytic ileus, obstructive disease of GI tract; Myasthaenia gravis. Precautions: Not recommended in children <12 years of age for the management of peptic ulcer; infants, patients with Down syndrome and children with spastic paralysis or brain damage may be hypersensitive to antimuscarinic effects. Use caution in elderly, patients with autonomic neuropathy, hepatic or renal disease, ulcerative colitis may…

Advice

Take 30-60 minutes before meals. Contact prescriber if there is headache, blurred vision, eye pain, dizziness, severe constipation, nervousness, flushing, difficulty in breathing, irregular heartbeat, confusion, mental excitation, lack of sleep, taste disturbance, dry mouth, loss of appetite, difficulty in urination, urinary retention, palpitations, decreased sweating, impotency. Empty bladder before taking medication. Take sufficient amount of fluids (2-3 litres per day) to maintain hydration, unless restricted by the prescriber. Sucking on lozenges may help to prevent dry mouth. Avoid direct sunlight. Use sunscreen, wear proper clothing and eyewear to prevent photosensitivity. Avoid…

Full information on Glycopyrrolate →

Interactions with Glycopyrrolate

Amantadine, cyclopropane, anticholinergic agents, levodopa.

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Compiled by Healify Pharmacy from published drug references. How we compile it →

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