Oxsoralen

by Haroon Bros

Active ingredients: Methoxsalen, Methoxsalen (Meladinine)

Packs

About Methoxsalen

Antipsoriasis

Uses

Psoriasis, idiopathic vitiligo (in conjunction with UV radiation or photosensitizing agent).

How to take it

ORAL: Take with milk or after food as a single dose, or in 2 divided doses, approx 30 min apart to minimize GI side effects. Idiopathic vitiligo: Adults & Children: Above 12 yr: 20 mg/day 2-4 hr before exposure to UVA or sunlight. Therapy should be on alternate days & never on 2 consecutive days. Max dose: 0.6 mg/kg. Psoriasis: Adults: 10-70 mg, 1.5-2 hr before exposure to UVA, administered 2-3 times wkly. TOPICAL: Vitiliginous lesions: Adults: The soln/cream after dilution to 0.1% or 0.01% applied once wkly for 6-9 mth. Surrounding skin should be protected by an opaque screen, the treated area should be exposed to UVA after waiting up to 2 hr. After exposure the lesions should be washed…

Side effects

Oedema, hypotension, nervousness, vertigo, depression, painful blistering, burning, pruritus, hypo-pigmentation, rash, cheilitis, erythema, itching, nausea, loss of muscle coordination.

Pregnancy and breastfeeding

Contraindications: Diseases associated with light sensitivity (lupus erythematosus, porphyria). Hypertension, heart, liver or kidney failure. Precautions: Protect eyes & skin against complementary sun exposure after controlled UV irradiation. Monitor patients on possible long-term risks of photo-chemotherapy e.g. skin aging, changes in pigmentation, risk of basal cell epithelioma & cataract.

Full information on Methoxsalen →

Interactions with Methoxsalen

Photosensitizing agents e.g. anthracin, coal tar, griseofulvin, phenothiazine, nalidixic acid, halogenated salicylamide, sulphonamides, tetracycline, thiazides, organic dyes.

Tell your pharmacist or doctor about every medicine you take, including herbal products.

Need Oxsoralen? Ask us to source Oxsoralen and our pharmacist will call you back.

Other brands with the same ingredients

More from Haroon Bros

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.