Norpace

by Searle

Active ingredient: Disopyramide

Packs

About Disopyramide

Cardiac Therapy

Uses

Cardiac arrhythmias.

How to take it

Ventricular arrhythmias: Adults: Max 400 mg every 6 hr (immediate release) in severe refractory ventricular tachycardia. Body weight < 50 kg: Immediate release, initial loading dose 200 mg if rapid onset required, maintenance 100 mg every 6 hr. Controlled release, maintenance dose 200 mg every 12 hr. Body weight > 50 kg: Immediate release, initial loading dose 300 mg if rapid onset required, maintenance 150 mg every 6 hr and if no response seen within 6 hr of loading dose, may increase maintenance dose to 200 mg every 6 hr. Controlled release, maintenance dose 300 mg every 12 hr. Children: Not recommended.

Side effects

Anticholinergic effects. Very rarely psychosis, jaundice, hypoglycaemia.

Pregnancy and breastfeeding

Pregnancy: Risk cannot be ruled out. Lactation: Contraindicated or not recommended. Contraindications: 2nd or 3rd degree AV block, sinus node disease in absence of pacemaker. Cardiogenic shock. Severe uncompensated cardiac failure. Precautions: 1st degree AV block. Cardiac failure should be controlled with glycosides. Renal or hepatic failure. Prostatic hypertrophy, glaucoma, urinary retention, hypokalaemia.

Advice

Do not stop taking medication suddenly. Take a missed dose as soon as you remember, unless it is nearly time for the next dose. Do not double the dose. Inform prescriber if more than one dose is missed. Check pulse rate regularly and report important changes. Change position slowly from lying or sitting position to reduce dizziness. Avoid too much heat and exercise.

Full information on Disopyramide →

Interactions with Disopyramide

Other antiarrhythmics, beta-blockers, diuretics, anticholinergics.

Tell your pharmacist or doctor about every medicine you take, including herbal products.

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More from Searle

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.