Modlip Z
by Wilshire
Active ingredients: Ezetimibe, Simvastatin, Simvastatin and Ezetimibe
Packs
- Tab · 10/10 mg · 10's (049986)
- Tab · 20/10 mg · 10's (049987)
In stock at Healify — same active ingredient
- Simbex — from PKR 368
Always confirm a substitution with your pharmacist.
About Ezetimibe
Hypolipidaemic/Anti-atheroma
Uses
Adjunct to diet in primary hypercholesterolaemia either co-administered with a statin for patients not appropriately controlled with a statin alone, or as monotherapy when a statin is inappropriate or not tolerated. Adjunct to diet in homozygous familial hypercholesterolaemia in combination with a statin and, if necessary, other adjunctive treatments. Adjunct to diet in homozygous familial sitosterolaemia.
How to take it
Adults: 1 tab daily. Children: Under 10 yr, not recommended. Adjunct to statin treatment in primary hypercholesterolaemia and homozygous familial hypercholesterolaemia, ezetimibe alone in primary hypercholesterolaemia if statin inappropriate or not tolerated; adjunct to dietary measures in homozygous sitosterolaemia: 10-18 yr, 10 mg once daily.
Side effects
Headache, abdominal pain, diarrhoea, GI upset, fatigue, abnormal LFTs.
Pregnancy and breastfeeding
Pregnancy: Risk cannot be ruled out. Lactation: Contraindicated or not recommended. Contraindications: Moderate to severe hepatic impairment, concomitant use with a statin in active liver disease. Precautions: Monitor liver function if giving with a statin. Unexplained muscle weakness or pain; monitor creatine kinase levels if myopathy suspected.
Advice
Take with or without meals. Take medication at the same time each day. Take 2 hours before or 4 hours after bile acid binding agents. Contact prescriber if there is chest pain, palpitations, muscle pain, weakness, skeletal pain, joint pain or increased sweating. Take low-cholesterol diet. Exercise regularly. Try to lose weight.
Full information on Ezetimibe →
Interactions with Ezetimibe
Fibrates, cyclosporin, cholestyramine, colestipol, anticoagulants.
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Compiled by Healify Pharmacy from published drug references. How we compile it →
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