Apxan
by Ferozsons
Active ingredient: Apixaban
Packs
- Tab · 2.5 mg · 30's
- Tab · 5 mg · 30's
In stock at Healify — same active ingredient
Always confirm a substitution with your pharmacist.
About Apixaban
Anticoagulant/Antiplatelet
Uses
Reduction of risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation. Prophylaxis of DVT, which may lead to pulmonary embolism, in patients who have undergone hip or knee replacement surgery. Treatment of DVT and PE and for the reduction in the risk of recurrent DVT and PE following initial therapy.
How to take it
ORAL: Reduction of risk of stroke and systemic embolism in nonvalvular atrial fibrillation: Adults: 5 mg twice daily. In patients with at least 2 of the following characteristics: Age =80 yrs, body wt. =60 kg, or serum creatinine =1.5 mg/dL, the recommended dose is 2.5 mg twice daily. Prophylaxis of DVT following hip or knee replacement surgery: 2.5 mg twice daily. Treatment of DVT and PE: 10 mg twice daily for 7 days, followed by 5 mg twice daily. Reduction in the risk of recurrent DVT and PE following initial therapy: 2.5 mg twice daily.
Side effects
Increased risk of thrombotic events after premature discontinuation. Prolonged bleeding. Skin rash (rare).
Pregnancy and breastfeeding
Pregnancy: Contraindicated in pregnancy. Lactation: Contraindicated or not recommended. Contraindications: Severe hepatic impairment. Patients with artificial heart valves. Anti-phospholipid syndrome, esp. with positive triple antibody testing, who have a history of blood clots. Precautions: Monitor patients frequently for signs and symptoms of neurological impairment (e.g. numbness/weakness of the legs, bowel/bladder dysfunction).
Advice
Take with or without meals. Do not stop taking medication abruptly. Contact prescriber right away if you experience unusual bleeding from the gums, nosebleeds that happen often, menstrual/vaginal bleeding heavier than normal, red/pink/brown urine, red/black stool, vomit blood, unexpected pain/swelling/joint pain, headaches, feeling dizzy/weak, difficulty in breathing.
Full information on Apixaban →
Interactions with Apixaban
NSAIDs, antiplatelets, thrombolytics, dextran, sulfinpyrazone, vit K antagonists, strong CYP3A4/P-gp inhibitors (e.g. azole antifungals, HIV protease inhibitors) and inducers (e.g. rifampicin, phenytoin, carbamazepine, phenobarbital).
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Compiled by Healify Pharmacy from published drug references. How we compile it →
Always consult a pharmacist or doctor.