Fraizeron

by Novartis/Nouveaux

Active ingredient: Secukinumab

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About Secukinumab

Cytostatic

Uses

Moderate to severe plaque psoriasis.

How to take it

Adults: 300 mg by SC inj, repeated once weekly at weeks 1, 2 and 3 then monthly starting at week 4. Consider discontinuation if no response after 16 weeks. Children: Not recommended. Administer via SC route. Reconstitution: Reconstitute with SWFI. The resulting solution should be clear and colourless to slightly yellow. Stability: Store in a refrigerator (2°C-8°C). Do not freeze. Protect from light.

Side effects

Upper RTI, diarrhoea, rhinorrhoea, oral herpes.

Pregnancy and breastfeeding

Pregnancy: Contraindicated in pregnancy. Lactation: Contraindicated or not recommended. Contraindications: Clinically important, active infection, including TB. Precautions: Crohn’s disease. Renal or hepatic impairment. Latent TB; consider treatment before starting secukinumab. Latex sensitivity. Chronic infection or history of recurrent infection. Advise patients to report any signs of infection; discontinue if severe infection occurs.

Full information on Secukinumab →

Interactions with Secukinumab

Live vaccines, CYP3A4 substrates, other immunosuppressants.

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Compiled by Healify Pharmacy from published drug references. How we compile it →

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