Thiocolchicoside

Muscle Relaxant · Skeletal muscle relaxant

Indications

Acute and chronic low back and sciatic pain, cervicobrachial neuralgia, refractory torticollis, post-traumatic and post-operative painful syndromes. Spastic sequela of hemiparesis, Parkinson's disease and Parkinsonism caused by drugs, with special reference to the neurodysleptic syndrome.

Dosage

ORAL: Adults: Two cap after the main meals. Children: Not recommended. INJECTION: Adults: Two amp by IM inj over a period of 24 hr. Children: Not recommended.

Adverse Effects

Diarrhoea.

Risk Factor (Pregnancy/Lactation)

Pregnancy: Risk cannot be ruled out. Lactation: Contraindicated or not recommended. Contraindications: Flaccid paralysis, muscular hypotonia. Precautions: If oral administration causes diarrhoea, posology must be properly reduced.

Pharmacokinetics

Absorption: Oral: Rapidly absorbed. Metabolism: Firstly, in the intestine to inactive metabolite then further metabolized to active metabolite in blood circulation. Bioavailability: Oral: Approx. 25%. Half-life elimination: Oral: Approx. 7.7 hrs. IM: 1 hr. Time to peak, plasma: IM: 30 mins. Excretion: Urine (20%). Faeces (79%).

Brands with this active ingredient

• Amuze
• Bruspaz
• Caelyx
• Cidekel
• Colchilax
• Colchis
• Colril
• Colval
• Corelex
• Ezoside
• Fachico
• Keloside
• Mucogin
• Muscide
• Muscolin

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.