Enoxacin
Quinolone · Quinolone
Indications
Infections of respiratory tract, ENT, skin and soft tissues, abdominal cavity, pelvis minor, kidney, urinary tract and genital organs.
Dosage
Adults: 400 mg twice daily for 7-14 days. Gonococcal urethritis: Single dose of 400 mg. Children: Not recommended.
Risk Factor (Pregnancy/Lactation)
Pregnancy: Contraindicated in pregnancy. Lactation: Contraindicated or not recommended. Contraindications: Children in growth phase, epileptics, hypersensitivity to quinolones.
Interactions
Aluminum, calcium or magnesium containing antacids, didanosine, ferrous sulphate, magnesium containing laxatives, sucralfate, zinc, bismuth, cyclosporine, digoxin, NSAIDs, theophylline, warfarin, caffeine.
Advice to Patient
Take 1 hour before or 2 hours after meals, with a full glass of water. Do not take aluminium-, calcium-, or magnesium-containing antacids, bismuth, didanosine (chewable or buffered tablets), if prescribed or products that contain iron or zinc for 8 hours before or 2 hours after taking enoxacin. If you have missed a dose, take it as soon as you remember, unless it is nearly time for the next dose. Do not double the dose. Inform prescriber if there is tendon pain or inflammation and discontinue medication, and rest until tendinitis or tendon rupture is gone. Discontinue medication if rash develops or if there are signs of allergy. Complete full course of therapy even if you feel better. Avoid caffeine intake during therapy. Avoid direct sunlight, wear sunscreen, proper eyewear and protective clothing to prevent photosensitivity.
Pharmacokinetics
Absorption: Rapidly absorbed following oral administration. Metabolism: Hepatic. Bioavailability: 90%. Half-life elimination: 3-6 hrs. Prolonged in renal impairment. Time to peak, plasma: 1-2 hrs. Excretion: Urine (mainly).
Brands with this active ingredient
Compiled by Healify Pharmacy from published drug references. How we compile it →
Always consult a pharmacist or doctor.