Cinitapride

Antiemetic & Gastroprokinetic · Gastroprokinetic

Indications

For the treatment of gastrointestinal disorders associated with motility disturbances such as gastro-oesophageal reflux disease, non-ulcer dyspepsia and delayed gastric emptying.

Dosage

Adults: 1 mg three times daily before meals. Children: Not recommended.

Adverse Effects

Drowsiness, diarrhoea, extrapyramidal effects, cutaneous reactions.

Risk Factor (Pregnancy/Lactation)

Pregnancy: Contraindicated in pregnancy. Lactation: Contraindicated or not recommended. Precautions: It enhances the action of acetylcholine. Use with caution to elderly, patients with a history of dyskinesia induced by neuroleptics. Drowsiness may occur.

Interactions

Atropine, drugs that enhance the effect of medicines used for the illness of CNS and for insomnia. Digoxin.

Pharmacokinetics

Absorption: Oral (12 mg): Rapid. IM (4 mg): More rapid. Half-life elimination: 3-5 hrs during the first 8 hrs and a residual half-life greater than 15 hrs thereafter. Time to peak, serum: Oral: Within 2 hrs. IM: Within 1 hr.

Brands with this active ingredient

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.