Flecra

by Nabiqasim

Active ingredient: Flecainide acetate

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About Flecainide Acetate

Cardiac Therapy

Uses

Tab: AV nodal reciprocating tachycardia. Wolff-Parkinson-White syndrome. Paroxysmal atrial fibrillation in patients with disabling symptoms. Symptomatic sustained ventricular tachycardia. Premature ventricular contractions and/or non-sustained ventricular tachycardia not responding to other therapy. Inj: Rapid control of resistant ventricular tachyarrhythmias, AV nodal reciprocating tachycardia, Wolff-Parkinson-White syndrome, paroxysmal atrial fibrillation in patients with disabling symptoms.

How to take it

Adults: ORAL: Supraventricular arrhythmias: Initially 50 mg twice daily; max 300 mg daily. Ventricular arrhythmias: Initially 100 mg twice daily; max 400 mg daily. Reduce after 3-5 days to lowest dose required to maintain control. Adults: INJECTION: Ventricular tachyarrhythmias resistant to other treatments: Slow IV injection: 2 mg/kg over 10-30 min, max 150 mg; followed by IV infusion at a rate 1.5 mg/kg/hr for 1 hr, subsequently reduced to 100-250 mcg/kg/hr up to 24 hr, max total dose in first 24 hr, 600 mg, transfer to oral treatment as mentioned above. Children: Under 12 yr, not recommended. Resistant re-entry supraventricular tachycardia, ventricular ectopic beats or ventricular…

Side effects

Photosensitivity, nausea, vomiting, dizziness, visual disturbances, elevated liver enzymes, jaundice. Allergic skin reactions, increased antinuclear antibodies. Decreased blood counts. Peripheral neuropathy paraesthesia, ataxia. Rarely corneal deposits, pneumonitis, urticaria, hallucinations, depression, confusion, amnesia, dyskinesia, convulsions.

Pregnancy and breastfeeding

Pregnancy: Risk cannot be ruled out. Lactation: Caution advised or effect undetermined. Contraindications: Cardiac failure, history of MI with asymptomatic ventricular arrhythmias, long standing atrial fibrillation where no attempt to convert sinus rhythm, haemodynamically significant valvular heart disease, 2nd or 3rd degree AV block, sinus node disease in absence of pacemaker, structural organic heart disease, abnormal left ventricular function. Precautions: Therapy should be initiated under hospital supervision. Correct electrolytes before admin. Pacemakers or temporary pacing electrodes. Renal or hepatic insufficiency; monitor plasma levels. Cardiac disease. Acute onset of atrial…

Advice

Take oral forms with or without meals. Take a missed dose as soon as you remember if it is within 6 hours of the scheduled time. Contact prescriber if there is palpitations, chest pain, acute nervousness, fatigue, headache, excessively slow or rapid heartbeat, unusual cough, unusual weight gain, swelling of hands or ankles, respiratory difficulty, muscle tremor, weakness or numbness. Do not stop taking medication suddenly, taper dosage gradually according to prescriber’s instructions. Learn how to take pulse and record it daily alongwith weight.

Full information on Flecainide Acetate →

Interactions with Flecainide Acetate

Other antiarrhythmics, amiodarone, digoxin, cardiac depressants, liver enzyme inducers, fluoxetine, TCADs, reboxetine, dolasetron, phenytoin, phenobarbital, carbamazepine, clozapine, mizolastine, terfenadine, quinine, protease inhibitors, diuretics, cimetidine, bupropion.

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Compiled by Healify Pharmacy from published drug references. How we compile it →

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