Estezene

by Adamjee

Active ingredients: Phenothiazine, Trifluoperazine

PKR 60

Available at Healify

Estezene Tablets 1Mg (1 Strip = 10 Tablets) · Strip · PKR 60 · In stock
Estezene Tablets 5Mg (1 Strip = 10 Tablets) · Strip · PKR 96 · In stock

Manufactured by ADAMJEE PHARMACEUTICALS.

About Trifluoperazine

Tranquilizer, Sedative/Hypnotic

Uses

Low dosage: Mild mental & emotional states; nausea & vomiting. High dosage: Schizophrenia, psychosis.

How to take it

Adults: Low dosage: 1 mg to 2 mg twice daily. High dosage: 5 mg to 20 mg daily in two doses. Children: Schizophrenia and other psychoses, short-term adjunctive management of psychomotor agitation, excitement and violent or dangerously impulsive behavior: 12-18 yr, initially 5 mg twice daily, increased by 5 mg daily after 1 wk, then at intervals of 3 days, according to response. Short-term adjunctive management of severe anxiety: 3-6 yr, up to 500 mcg twice daily; 6-12 yr, up to 2 mg twice daily; 12-18 yr, 1-2 mg twice daily, increased if necessary to 3 mg twice daily. Severe nausea and vomiting unresponsive to other antiemetics: 3-5 yr, up to 500 mcg twice daily; 6-12 yr, up to 2 mg twice…

Side effects

Leucopenia, thrombocytopenia, hyperprolactinaemia, acute dystonias and dyskinesias, Parkinsonism, drowsiness, insomnia, tachycardia, hypotension, erythemas, anticholinergic effects, anorexia, depression, rash, photosensitivity, convulsions, blood dyscrasias, extrapyramidal symptoms, agitation, mental dullness, dizziness, ECG changes. Rarely, agranulocytosis, jaundice, neuroleptic malignant syndrome (discontinue).

Pregnancy and breastfeeding

Pregnancy: Risk cannot be ruled out. Lactation: Contraindicated or not recommended. Contraindications: Comatose states, bone marrow depression, liver damage, blood dyscrasias, uncontrolled cardiac failure. Precautions: Elderly. Cardiovascular disease, undiagnosed vomiting, angina, arrhythmia, Parkinsonism, epilepsy, risk factors for stroke, QT prolongation or VTE. Renal or hepatic impairment. Narrow-angle glaucoma, myasthenia gravis, prostatic hypertrophy, extremes of temperature. Monitor for tardive dyskinesia, ocular changes, blood dyscrasias, hepatic impairment, cardiac conduction defects. Warn patients of impaired judgment and dexterity. Withdraw gradually. Elderly.

Advice

Take with meals. Do not take medication within 2 hours of taking an antacid. Discontinue medication and report immediately if there is difficulty in swallowing or speaking and tongue protrusion from mouth. Contact prescriber if there is severe dizziness, change in skin colour (gray-blue), change in vision, change in urinary pattern or unrelieved urinary retention, change in menstrual pattern, change in libido, chest pain, palpitations, fast heartbeat, swelling or pain in breasts (male or female), trembling in fingers, change in gait, increased sleepiness, anxiety, seizures, unusual movements, confusion, abnormal thoughts, change in personality, skin rash, skin irritation. Empty bladder…

Full information on Trifluoperazine →

Interactions with Trifluoperazine

Ephedrine, barbiturates, CNS depressants, anticholinergics, antacids, oral hypoglycaemias, antihypertensives, anticonvulsants, drugs that prolong QT interval, alcohol, dopaminergics, lithium, metoclopramide, desferrioxamine.

Tell your pharmacist or doctor about every medicine you take, including herbal products.