Epler

by Platinum

Active ingredient: Eplerenone

PKR 936

Available at Healify

Epler Tablets 50mg (1 Box = 1 Strip)(1 Strip = 10 Tablets) · Box · PKR 936 · In stock

Manufactured by PLATINUM PHARMACEUTICAL.

About Eplerenone

Diuretic

Uses

Adjunct in stable patients with left ventricular dysfunction with evidence of heart failure, following myocardial infarction (start therapy within 3-14 days of event).

How to take it

Adults: Initially 25 mg once daily, increased within 4 wk to 50 mg once daily. Children: Not recommended.

Side effects

Diarrhoea, nausea, flatulence, vomiting, hypotension, dizziness, hyperkalaemia, rash, atrial fibrillation, postural hypotension, arterial thrombosis, dyslipidaemia, pharyngitis, headache, insomnia, gynaecomastia, pyelonephritis, hyponatraemia, dehydration, eosinophilia, asthaenia, malaise, back pain, leg cramps, impaired renal function, azotaemia, sweating, hypercholesterolaemia, syncope, GI upset, left ventricular failure, atrial fibrillation, cough, pruritus, muscle spasms, raised blood urea and creatinine.

Pregnancy and breastfeeding

Pregnancy: Risk cannot be ruled out. Lactation: Caution advised or effect undetermined. Contraindications: Concomitant use of potassium-sparing diuretics or potassium supplements. Hyperkalaemia. Severe hepatic or renal impairment. Precautions: Monitor plasma potassium concentration before, during and after treatment. Elderly.

Advice

Take with or without meals at the same time each day. Contact prescriber if there is chest pain, palpitations, unusual cough or flu-like symptoms. Avoid potassium containing supplements or salt substitutes. Change position slowly.

Full information on Eplerenone →

Interactions with Eplerenone

ACE inhibitors, angiotensin II antagonists, potassium sparing diuretics, potassium supplements, CYP3A4 inhibitors or inducers, NSAIDs, lithium, cyclosporin, tacrolimus, trimethoprim, angiotensin II antagonists, alpha one blockers, TCADs, antipsychotics, amifostine, baclofen, digoxin, warfarin, glucocorticoids, tetracosactide.

Tell your pharmacist or doctor about every medicine you take, including herbal products.