Dytra

by Tabros

Active ingredient: Drotaverine

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About Drotaverine

Antispasmodic & Anticholinergic

Uses

Control and prevention of pain and dysfunction caused by smooth muscle spasm.

How to take it

INJECTION: Adults: 1-2 amp slowly by IV 1-3 time daily. Can also be administered intramuscularly and intra-arterially in peripheral arterial disease. Children: Not recommended. TABLET: Adults: Initially 80 mg followed by 40-80 mg three times daily. Children: Not recommended.

Side effects

Constipation, transient bradycardia (followed by tachycardia, palpitation and arrhythmias), reduced bronchial secretions, urinary urgency and retention, dilatation of the pupils with loss of accommodation, photophobia, dry mouth, flushing and dryness of the skin. Side-effects that occur occasionally include confusion (particularly in the elderly), nausea, vomiting and giddiness. Very rarely, angle-closure glaucoma may occur.

Pregnancy and breastfeeding

Pregnancy: Contraindicated in pregnancy. Lactation: Caution advised or effect undetermined. Contraindications: Antimuscarinics are contra-indicated in Myasthaenia gravis (but may be used to decrease muscarinic side-effects of anticholinesterases), paralytic ileus, pyloric stenosis, toxic megacolon and prostatic enlargement. Precautions: Antimuscarinics should be used with caution in Down's syndrome, in children and in the elderly; they should also be used with caution in gastro-esophageal reflux disease, diarrhoea, ulcerative colitis, autonomic neuropathy, acute myocardial infarction, hypertension, conditions characterised by tachycardia (including hyperthyroidism, cardiac insufficiency,…

Advice

Take with or without meals.

Full information on Drotaverine →

Interactions with Drotaverine

Amantadine, atenolol, digoxin, phenothiazines, tricyclic antidepressants.

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Compiled by Healify Pharmacy from published drug references. How we compile it →

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