Digitek
by Global/Vision
Active ingredient: Digoxin
Packs
- Tab · 250 mcg · 25's
About Digoxin
Cardiac Therapy
Uses
Digitalis therapy, particularly congestive heart failure.
How to take it
ORAL: Rapid digitalisation, Adults: 1-1.5 mg in divided doses over 24 hr; less urgent digitalisation, Adults: 250-500 mcg daily (higher dose may be divided). Maintenance, 62.5-500 mcg daily (higher dose may be divided) according to renal function and, in atrial fibrillation, on heart-rate response; usual range, 125-250 mcg daily (lower dose may be appropriate in elderly). INJECTION: Adults: Emergency loading dose by IV infusion, 0.75-1 mg over at least 2 hr, then maintenance dose by mouth on the following day. Children: Digitalizing Dose: Premature Infants: 20-30 mcg/kg orally or 15-25 mcg/kg IV. Full-Term Infants: 25-35 mcg/kg orally or 20-30 mcg/kg IV. 1-24 mth: 35-60 mcg/kg orally or…
Side effects
Usually associated with excessive dosage, include; anorexia, nausea, vomiting, diarrhoea, abdominal pain; visual disturbances, CNS disturbances, headache, fatigue, drowsiness, confusion, delirium, hallucinations, depression, arrhythmias, heart block, PR prolongation, sinus bradycardia, rarely rash, intestinal ischaemia, gynaecomastia on long-term use; thrombocytopenia reported.
Pregnancy and breastfeeding
Pregnancy: Risk cannot be ruled out. Lactation: Caution advised or effect undetermined. Contraindications: Intermittent complete heart block, second degree AV block; supra-ventricular arrhythmias caused by Wolff-Parkinson-White syndrome; hypertrophic obstructive cardiomyopathy (unless concomitant atrial fibrillation and heart failure but with caution), ventricular tachycardia, ventricular fibrillation. Elective electro-conversion. Precautions: AV block, acute MI, cardiac amyloidosis, constrictive pericarditis, beriberi heart disease, myocarditis, cation imbalance, hypercalcaemia, hypokalaemia, hypomagnesaemia, hypoxia, severe pulmonary disease, thyroid dysfunction, renal insufficiency,…
Advice
Take oral forms with or without meals. Take digoxin at same time each day to help increase compliance. Maintain sufficient dietary intake of potassium. Contact prescriber if there is loss of appetite, nausea, vomiting, swelling of extremities, persistent diarrhoea, abdominal discomfort, palpitations, blurred vision, yellowing of eyes, mental confusion, depression or unusual fatigue. Take pulse at the same time each day. Inform prescriber if pulse falls below 60 beats per minute or suddenly increases. Do not carry digoxin in anything other than its original labelled container. Use special dropper supplied with elixir to ensure accurate dose measurement. Take missed dose as soon as you…
Interactions with Digoxin
Diuretics, lithium, corticosteroids, carbenoxolone, lithium, other K+ depleting agents, alprazolam, amiodarone, gentamicin, indomethacin, itraconazole, captopril, verapamil, felodipine, tiapamil, flecainide, prazosin, propafenone, quinidine, quinine, beta-blockers, suxamethonium, spironolactone, tetracycline, erythromycin, trimethoprim, propantheline, adrenaline, antacids, kaolin, pectin, laxatives, cholestyramine, acarbose, salbutamol, diphenoxylate, sulphasalazine, neomycin, rifampicin, cytostatics, phenytoin, metoclopramide, penicillamine, calcium inj or supplement, other cardiac glycosides, St. John's Wort, vit D analogues, bupropion.
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Compiled by Healify Pharmacy from published drug references. How we compile it →
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