Caverject

by Pfizer

Active ingredient: Alprostadil

Packs

About Alprostadil

Erectile Dysfunction Products

Uses

Treatment and diagnosis of erectile dysfunction.

How to take it

Inj: Adults: Initially 2.5 mcg by intra-cavernosal injection. If necessary increase in 2.5 mcg increments to max 60 mcg. Max frequency of use, once daily and 3 times per wk. Children: Not applicable. Suppository: Adults: Initially 250 mcg by intraurethral administration. Increase or decrease for subsequent doses according to response. Max 2 doses in 24 hr and not more than 7 doses in 7 days. See literature. Children: Not recommended. The intracavernosal injection must be done under sterile conditions. The injection site is usually along the dorsolateral aspect of the proximal third of the penis. Avoid visible vein. Alternate the side of the penis that is injected and the injection site,…

Side effects

Inj: Burning sensation or tension in penis during erection. Fibrosis, erythema, testicular or perineal pain, penile deviations, haemosiderin deposits in penis. Priapism. Changes in blood pressure, cardiac arrhythmias, dizziness, headache, vagal shock, collapse. Suppository: Penile pain. Haematoma and other injection sites reactions. Fibrosis, erythema, testicular or perineal pain, penile deviations, haemosiderin deposits in penis, Peyronie's disease. Priapism. Muscle spasm. Changes in BP, cardiac arrhythmias, dizziness, headache, peripheral vascular disorders. Urethral application; urethral irritation.

Pregnancy and breastfeeding

Contraindications: Inj: Sickle cell anaemia, multiple myeloma, leukaemia. Suppository: Predisposition to prolonged erection (for e.g. in sickle cell anaemia, multiple myeloma, leukaemia), penile implants, abnormal penile anatomy (for e.g. severe hypospadia, severe curvature, cavernosal fibrosis, Peyronie's disease), balanitis, urethritis. Precautions: Inj: Advise patient to seek medical attention if erection persists for more than four hours. Angulation, phimosis, cavernosal fibrosis, Peyronie's disease. Suppository: Priapism; advise patients to seek medical help if erection last over 4 hours. Anatomical deformation of penis. Transient ischaemic attacks, unstable cardiovascular disorders.

Advice

Do not use more than 3 times per week. A gap of 24 hours must be given between injections. Contact prescriber if there are penile problems (such as nodule, pain, rash, redness, bruising, swelling, numbness, abnormal ejaculations, infection), hypotension or hypertension, palpitations, irregular heartbeat, chest pain, fever, flu or flu like symptoms, flushing, difficulty in breathing, wheezing. Avoid alcohol during therapy. Discontinue medication and inform prescriber immediately if erection remains for more than 4 hours or if there is severe penile pain. If you are using suppository, urinate just before inserting suppository and insert it with applicator supplied with drug. Use condom to…

Full information on Alprostadil →

Interactions with Alprostadil

Inj: Warfarin, heparin. Suppository: Other erectile dysfunction agents, sympathomimetics.

Tell your pharmacist or doctor about every medicine you take, including herbal products.

Need Caverject? Ask us to source Caverject and our pharmacist will call you back.

More from Pfizer

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.