C-Penem

by Maxitech

Active ingredient: Imipemide

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In stock at Healify — same active ingredient

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About Imipemide

Other Anti-infective Preps

Uses

Lower respiratory tract, intra-abdominal, genito- urinary, gynaecological, bone and joint, skin and soft tissue infections. Septicaemia. Prophylaxis of post-operative infections.

How to take it

Adults: IV: Usually 250 mg-1 gm by IV infusion 6-8 hourly, depending on type and severity of infections. Prophylaxis, 1 gm on induction of anaesthesia then 1 gm three hr later. IM: Adults: Usually 500-750 mg by deep IM inj 12 hourly depending on type and severity of infection; max 1.5 gm daily. Children: Under 3 mth, not recommended; over 3 mth, 15 mg/kg body weight every 6 hr. Max daily dose 2 gm. Gonococcal urethritis or cervicitis: Adults: 500 mg as a single dose. Children: Not recommended. IV: Administer by IV intermittent infusion; final concentration should not exceed 5 mg/mL; in fluid-restricted patients, a final concentration of 7 mg/mL has been administered; dose < 500 mg may be…

Side effects

Nausea, vomiting, diarrhoea. Colitis. Blood dyscrasias, elevated liver enzymes, urea and creatinine. CNS disturbances, convulsions, thrombophlebitis, eosinophilia, positive Coombs test.

Pregnancy and breastfeeding

Pregnancy: Risk cannot be ruled out. Lactation: Contraindicated or not recommended. Precautions: Penicillin hypersensitivity, GI disease (particularly colitis), CNS disorders, renal dysfunction. Monitor liver function.

Advice

This medication is administered by injection or infusion. Contact prescriber if there is redness/swelling/warmth/irritation at infusion or injection site or if there is dizziness, hallucinations, change in vision, anxiety, swelling of tongue/face/lips/throat, fever, chills, odd-smelling vaginal discharge or urine. Take sufficient amount of fluids (2-3 litres per day) to maintain hydration, unless restricted by the prescriber.

Full information on Imipemide →

Interactions with Imipemide

Probenecid, ganciclovir. valganciclovir, valproate, oral anticoagulants, agents that lower seizure threshold.

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Compiled by Healify Pharmacy from published drug references. How we compile it →

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