Bosmon

by Hilton

Active ingredient: Bosentan monohydrate

PKR 1,955

Available at Healify

Bosmon Tablets 62.5mg (1 Box = 14 Tablets) · Box · PKR 1,955 · In stock

Manufactured by HILTON PHARMA.

Other packs (not sold online by Healify)

Tab · 125 mg · 14's (066964)

About Bosentan Monohydrate

Cardiac Therapy

Uses

Pulmonary arterial hypertension to improve exercise capacity and symptoms in patients with grade II and III functional status. Systemic sclerosis with ongoing digital ulcer disease to reduce the number of new digital ulcers.

How to take it

Hypertension: Adults: Initially 62.5 mg twice daily for 4 wk, increasing to maintenance of 125 mg twice daily. Some patients may benefit from 250 mg twice daily. Max: 500 mg/day. Children: Not recommended. Systemic sclerosis: Adults: Initially 62.5 mg twice daily for 4 wk, increasing to maintenance of 125 mg twice daily. Children: Not recommended.

Side effects

Headache, flushing, abnormal hepatic function, anaemia, infected skin ulcer, urinary tract infection, dyspnoea, GI upset, erythema, dermatitis, pain in extremity, back pain, peripheral oedema, hepatic disorders, syncope, palpitations, hypotension, GORD, erythema, nasal congestion.

Pregnancy and breastfeeding

Pregnancy: Contraindicated in pregnancy. Lactation: Contraindicated or not recommended. Contraindications: Moderate to severe hepatic impairment, hepatic aminotransferase levels >3x upper limit. Precautions: Severe pulmonary arterial hypertension. Raised liver enzymes; monitor prior to and at monthly intervals during therapy and two weeks after any increase in dose. Advise patients to report any signs suggestive of liver damage. Monitor haemoglobin prior to and at monthly intervals during therapy for first 4 months and quarterly thereafter. Monitor for signs of fluid retention. Women of childbearing potential should use non-hormonal contraception during treatment; perform monthly pregnancy…

Advice

Take with or without meals. Contact prescriber immediately if there is hepatic dysfunction, including yellow skin or eyes, fever, nausea, vomiting, fatigue or abdominal pain. Do not miss follow-up tests.

Full information on Bosentan Monohydrate →

Interactions with Bosentan Monohydrate

CYP3A4 inhibitors (particularly potent inhibitors e.g. ketoconazole, itraconazole, ritonavir) or CYP3A4 inducers, CYP2C9 inhibitors (voriconazole, fluconazole), contraceptives, cyclosporin, rifampicin, glibenclamide, tacrolimus, sirolimus, sildenafil, tadalafil, simvastatin, immunosuppressants, warfarin, protease inhibitors, nevirapine.

Tell your pharmacist or doctor about every medicine you take, including herbal products.

Other brands with the same ingredients

Bozpah