Vorteil

by Wilshire

Active ingredient: Valdecoxib

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About Valdecoxib

Anti-rheumatic, Systemic

Uses

Osteoarthritis, rheumatoid arthritis, primary dysmenorrhoea.

How to take it

Adults: Osteoarthritis, rheumatoid arthritis: 10 mg once daily; max 20 mg once daily. Dysmenorrhoea: 40 mg once daily. On first day of treatment an additional 40 mg dose may be taken if necessary. Max 40 mg once daily. Children: Not recommended.

Side effects

Dry mouth, hypertension, peripheral oedema, GI upset, insomnia, somnolence, anaemia, respiratory symptoms, skin reactions. UTIs.

Pregnancy and breastfeeding

Pregnancy: Positive evidence of risk: Use only when no safer alternative exists for a serious problem. Lactation: Contraindicated or not recommended. Contraindications: Hypersensitivity to sulphonamides, aspirin/anti-inflammatory induced allergies. Active peptic ulcer or GI bleeding, inflammatory bowel disease. Severe congestive heart failure, severe hepatic impairment. Women attempting to conceive. Precautions: Moderate hepatic impairment, renal impairment, by-pass surgery. Serious skin reactions (discontinue). Hypertension, cardiac failure or other conditions predisposing to fluid retention. Dehydration. Surgical wounds. Elderly.

Advice

Take with or without meals. To prevent GI upset, take with meals. Discontinue medication and inform prescriber immediately if there is constant stomach pain, cramps, unusual bruising or bleeding, blood in stool/vomitus/urine. Contact prescriber if there is difficulty in breathing, skin rash, muscle pain, unusual fatigue, skin rash, lethargy, yellowing of skin or eyes, flu-like symptoms, sudden weight gain, changes in urinary pattern. Do not take with antacids. Avoid alcohol during therapy. Do not take aspirin or other medications during therapy without consulting prescriber. Take sufficient amount of fluids (2-3 litres per day) to maintain hydration, unless restricted by the prescriber.

Full information on Valdecoxib →

Interactions with Valdecoxib

Warfarin, other anticoagulants, antihypertensives cyclosporin, tacrolimus, rifampicin, lithium, oral contraceptives, inhibitors or substrates of CYP3A4, 2C9, 2C19 or 2D6.

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More from Wilshire

Compiled by Healify Pharmacy from published drug references. How we compile it →

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