Syntox

by Brookes

Active ingredient: Oxytocin

Packs

In stock at Healify — same active ingredient

Always confirm a substitution with your pharmacist.

About Oxytocin

Labour Inducer/Inhibitor

Uses

Induction of labour in case of post maturity, premature rupture of membranes or pre-eclampsia. Primary and secondary uterine inertia. Caesarean section. Postpartum haemorrhage, postpartum uterine atony.

How to take it

Adults: Induction or enhancement of labour: IV drip infusion of a 5% dextrose solution containing 1 IU syntocinon per 100 mL. The initial infusion rate of 1-4 milliunits/min equal to 0.1-0.4 mL/min (2-8 drops/min) may be gradually increased until the desired response is achieved (max 20 milliunits/min equal to 2 mL/min) or 40 drops/min) provided the foetal heart rate and the frequency and duration of contractions are carefully monitored. Third stage of labour and puerperium (haemorrhage, subinvolution of the uterus): 5-10 IU IM or 5 IU slowly IV. Caesarean section: 5 IU intramurally after delivery of the foetus. See literature. Children: Not recommended. Incomplete or inevitable abortion:…

Side effects

Very occasionally prolonged or too rapid infusion of Syntocinon has antidiuretic effects, which may cause transient water intoxication, with headaches and nausea.

Pregnancy and breastfeeding

Pregnancy: Contraindicated in pregnancy. Lactation: Caution advised or effect undetermined. Contraindications: Cephalopelvic disproportion, abnormal presentation. Excessive distension of the uterus (e.g. in multiple pregnancy, hydramnios), parity greater than 4, elderly multiparae, previous Caesarean section or other surgery involving the uterus. Severe toxaemia, predisposition to amniotic fluid embolism (foetal death in utero, abruption placentae), hypertonic contractions, placenta previa.

Advice

Check blood pressure regularly during therapy and inform prescriber about changes.

Full information on Oxytocin →

Interactions with Oxytocin

Prostaglandins.

Tell your pharmacist or doctor about every medicine you take, including herbal products.

Need Syntox? Ask us to source Syntox and our pharmacist will call you back.

Other brands with the same ingredients

More from Brookes

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.