Avecare

by Medera

Active ingredient: Ceftriaxone

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About Ceftriaxone

Cephalosporin

Uses

Severe respiratory and genitourinary tract, bone and joint, abdominal infections, sepsis, meningitis.

How to take it

Adults: Usually 1 gm daily by deep IM, slow IV inj over at least 2-4 min, or IV infusion. Severe infections, 2-4 gm as a single dose every 24 hr. Children: Usually 20-50 mg/kg once daily by IM inj, slow IV inj over at least 2-4 min, or IV infusion. Severe infections, up to max 80 mg/kg daily (max 50 mg/kg in neonates). Doses over 50 mg/kg to be given by slow IV infusion over at least 30 min. Peri-op prophylaxis: Adults: 1 gm as single IM or slow IV dose. Colorectal surgery: Adults: 2 gm by IM, slow IV inj or infusion with anaerobic antibacterial. Lower Respiratory Infection: Adults: IM/IV: Usual: 1-2 gm once daily (or in equally two divided doses). Max: 4 gm/day. Otitis Media: Children: 50…

Side effects

GI upset, skin reactions, blood dyscrasias. Rarely pseudomembranous colitis, raised liver enzymes, glucosuria, oliguria, haematuria, bronchospasm, phlebitis at inj site, urinary and biliary precipitates, pancreatitis, nephrolithiasis, haemolytic anaemia, positive Coombs test.

Pregnancy and breastfeeding

Pregnancy: No evidence of risk in humans. Lactation: Caution advised or effect undetermined. Contraindications: Beta-lactam hypersensitivity. Premature newborns having less than 41 weeks postmenstrual age; neonates over 41 weeks postmenstrual age with jaundice, hypoalbuminaemia or acidosis; concomitant treatment with IV calcium (including total parenteral nutrition containing calcium) in neonates over 41 weeks postmenstrual age - risk of precipitation in urine and lung. Do not use in hyperbilirubinaemia neonates. Precautions: Severe renal and hepatic impairment. Do not use in pregnancy unless absolutely indicated. Monitor FBC during prolonged treatment. Non-severe hypersensitivity to other…

Advice

This medication is to be administered by injection or infusion only. Contact prescriber if there is burning/swelling/redness/pain at injection or infusion site or if there is rash, hives, itching, difficulty in breathing or if there is swallowing, severe unrelieved diarrhoea, vaginal drainage or itching, mouth sores, blood, pus or mucus in stool or urine, easy bruising or bleeding, unusual chills or fever. Watery or bloody stools can occur 2 or more months after therapy and can be serious, requiring immediate treatment. Take sufficient amount of fluids (2-3 litres per day) to maintain hydration, unless restricted by the prescriber.

Full information on Ceftriaxone →

Interactions with Ceftriaxone

Oral contraceptives, calcium containing IV solns.

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Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.