Progace

by Medinet

Active ingredient: Megestrol acetate

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About Megestrol Acetate

Cytostatic

Uses

Endometrial or breast carcinoma. Anorexia or cachexia associated with AIDS.

How to take it

Adults: Breast carcinoma: 160 mg daily in single or divided doses. Endometrial carcinoma: 40-320 mg daily in divided doses. Both for minimum period of 2 mth. Anorexia or cachexia associated with AIDS: Susp: Initially, 625 mg daily (of the 125 mg/mL susp) or 800 mg daily (of the 40 mg/mL susp). Children: Not applicable.

Side effects

Weight gain, nausea, urticaria, tumour flare, adrenal insufficiency, Cushingoid effects, diabetes, increased appetite, altered mood, carpal tunnel syndrome, lethargy, cardiac failure, thrombophlebitis, pulmonary embolism, hypertension, hot flushes, dyspnoea, GI upset, rash, alopecia, pollakiuria, menorrhagia, erectile dysfunction, asthenia, pain, oedema.

Pregnancy and breastfeeding

Pregnancy: Contraindicated in pregnancy. Lactation: Contraindicated or not recommended. Precautions: Thrombophlebitis. Severe hepatic impairment. Elderly; consider monitoring renal function.

Advice

Take with meals. Swallow whole with a glass of water. Discontinue medication and report immediately if you are taking this medication for prevention of malaria and you feel confusion, depression, anxiety, nervousness or restlessness. Contact prescriber if you experience changes in vision, CNS changes, unusual fatigue, severe constant GI upset, changes in hearing, ringing in ears. Avoid alcohol during therapy. Regular eye examinations (every 4-6 months) are required during long term therapy.

Full information on Megestrol Acetate →

Interactions with Megestrol Acetate

Folate inhibitors.

Tell your pharmacist or doctor about every medicine you take, including herbal products.

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Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.