Prasumac

by Mcolson

Active ingredient: Prasugrel

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About Prasugrel

Anticoagulant/Antiplatelet

Uses

In combination with aspirin for the prevention of atherothrombotic events in patients with acute coronary syndrome undergoing percutaneous coronary intervention.

How to take it

Adults: (with aspirin) Initially 60 mg as a single dose then body-weight over 60 kg, 10 mg once daily or body-weight under 60 kg, or Elderly over 75 yr, 5 mg once daily. Children: Not recommended.

Side effects

Haemorrhage (including gastrointestinal and intracranial), haematoma; haematuria; anaemia; rash, contusion.

Pregnancy and breastfeeding

Pregnancy: Risk cannot be ruled out. Lactation: Caution advised or effect undetermined. Contraindications: Active bleeding; history of stroke or transient ischaemic attack. Severe hepatic impairment. Precautions: Patients at increased risk of bleeding (e.g. from recent trauma, surgery, gastro-intestinal bleeding, or active peptic ulcer disease); concomitant use of drugs that increase risk of bleeding; discontinue at least 7 days before elective surgery if antiplatelet effect not desirable; elderly; body-weight less than 60 kg. Renal impairment, mild to moderate hepatic impairment.

Advice

Take with or without meals. Take daily dose of aspirin as prescribed. Contact prescriber if unusual bleeding or bruising occurs. Due to risk of bleeding, avoid using NSAIDs including OTC medications. To prevent bleeding, use soft toothbrush, floss with waxed floss, use electric razor, avoid scissors or sharp knives and harmful activities.

Full information on Prasugrel →

Interactions with Prasugrel

NSAIDs, heparin, phenindione, clopidogrel, oral anticoagulants, fibrinolytics, cyclophosphamide, efavirenz.

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Compiled by Healify Pharmacy from published drug references. How we compile it →

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