Phenida

by Zafa

Active ingredient: Methylphenidate

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About Methylphenidate

Other CNS Drugs

Uses

Attention-deficit hyperactivity disorder (ADHD); narcolepsy.

How to take it

Attention-deficit hyperactivity disorder (ADHD): Adults: 10-60 mg/day divided 2-3 doses. Discontinue if no response after 1 mth. Narcolepsy: 10-60 mg (usually 20-30 mg) daily in divided doses before meals. Children: Not recommended for children under 6 yr; doses over 60 mg daily not recommended. Attention deficit hyperactivity disorder: 4-6 yr: 2.5 mg twice daily increased if necessary at weekly intervals by 2.5 mg daily to max 1.4 mg/kg daily in 2-3 divided doses, discontinue if no response after 1 mth; 6-18 yr, initially 5 mg 1-2 times daily, increased if necessary at weekly intervals by 5-10 mg daily, max 60 mg daily (licensed) in 2-3 divided doses but may be increased to 2.1 mg/kg daily…

Side effects

Nervousness, insomnia, headache, dizziness, dyskinesia, blurring of vision, cramps, abdominal pain, nausea, vomiting, tachycardia, palpitation, arrhythmia, changes in blood pressure, heart rate, rash, pruritus, urticaria, fever, arthralgia, moderately reduced weight gain and minor retardation of growth in stature may occur in children during prolonged therapy, anorexia, GI upset, drowsiness, dry mouth, pyrexia, nasopharyngitis, alopecia, tics, cough, pharyngolaryngeal pain, mood and behavioural disturbances, bruxism, fatigue, increased ALT. Cerebral vasculitis, erectile dysfunction, blood dyscrasias.

Pregnancy and breastfeeding

Pregnancy: Risk cannot be ruled out. Lactation: Caution advised or effect undetermined. Contraindications: Anxiety and tension states, agitation, a family history or diagnosis of Tourette's syndrome, glaucoma, hyperthyroidism, cardiac arrhythmia, severe angina pectoris, hypersensitivity to methylphenidate. Treatment of severe depression. Phaeochromocytoma. Diagnosis or history of severe mood disorders, schizophrenic symptoms, anorexia nervosa, psychopathological personality disorder, aggression, suicidal tendency. Precautions: In psychotic patients this drug may exacerbate symptoms of behavioural disturbances and thought disorders. Prolonged use can lead to marked tolerance, psychic…

Advice

Take tablets and sustained-release tablets 30-45 minutes before meals with a full glass of water. Do not divide or chew or crush sustained release dosage forms, swallow whole. Do not crush or chew capsule contents. Contact prescriber if there is dizziness, tremors, nervousness, lack of sleep, increased agitation, unrelieved fast heartbeat, skin rash, skin irritation, black coloured stool, change in gait or movement. Avoid alcohol, caffeine and other stimulants during therapy. Take sufficient amount of fluids (2-3 litres per day) to maintain hydration, unless restricted by the prescriber. Taking small, frequent meals may help to maintain nutritional status.

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Interactions with Methylphenidate

Hypertensives, antihypertensives, MAOIs, tricyclic antidepressants, coumarin, some anticonvulsants and phenylbutazone, SSRIs, pressor agents, guanethidine, alcohol, clonidine, haloperidol, dopaminergics, anaesthetics.

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Compiled by Healify Pharmacy from published drug references. How we compile it →

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