Otim

by Neutro

Active ingredient: Cefuroxime

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About Cefuroxime

Cephalosporin

Uses

Respiratory tract, skin and soft tissue infections; serious infections pending bacteriology. Meningitis. Prophylaxis against infection in surgical procedures. UTI and gonorrhoea.

How to take it

ORAL: Adults: Most infections and bronchitis, usually 250 mg twice daily. Severe infections and pneumonia: 500 mg twice daily. Gonorrhoea: 1 gm as a single dose. Children: 3-6 mth (4-6 kg body wt): 40-60 mg; 6 mth-2 yr, 60-120 mg; 2-12 yr: 125 mg. All twice daily. Lower Respiratory Infection: Adults & Children: >13 yr: 250-500 mg twice daily for 5-10 days. Upper Respiratory Infection: Pharyngitis/Tonsillitis/ Sinusitis: Adults: 250 mg every 12 hr for 10 days. Children: >13 yr: 250 mg every 12 hr for 10 days. Pharyngitis/Tonsillitis: Children: 3 mth-12 yr, 125 mg every 12 hr for 10 days or 10 mg/kg every 12 hr for 10 days. Max: 500 mg/day. Sinusitis: Children: 3 mth-12 yr, 250 mg every 12 hr…

Side effects

Hypersensitivity reactions, Gl disturbances. Rarely pain at inj site, candidiasis, eosinophilia, neutropenia, leucopenia, transient rise in liver enzymes, blood urea. Positive Coomb's test, headache, dizziness, candida overgrowth, decreased haemoglobin, pseudomembranous colitis, haemolytic anaemia.

Pregnancy and breastfeeding

Pregnancy: No evidence of risk in humans. Lactation: Contraindicated or not recommended. Precautions: Penicillin hypersensitivity. Renal impairment (CrCl<20 mL/min). Suspension may contain aspartame; caution in phenylketonuria. Lyme disease, warn patient of Jarisch-Herxheimer reaction.

Advice

Take with or without meals. Take at regular intervals, as scheduled. Shake oral suspension well before measuring and use a calibrated measuring device to ensure accurate dose. To improve flavour of oral suspension, refrigerate it but do not freeze. For using single-dose packet, empty contents of one packet into a glass and add at least 10 mL (2 tsp) of cold water, apple, grape or orange juice or lemonade. Stir well and take whole mixture at once. Contact prescriber if there is burning/swelling/redness/pain at injection or infusion site or if there is chest pain, difficulty in breathing or swallowing, severe unrelieved diarrhoea, vaginal drainage or itching, mouth sores, bloody stool, bloody…

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Interactions with Cefuroxime

Loop diuretics, aminoglycosides. Probenecid, combined oral contraceptives, drugs affecting gastric acidity, oral anticoagulants.

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Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.