Nixaf

Nixaf

by Sami

Active ingredient: Rifaximin

PKR 420

Available at Healify

Manufactured by SAMI PHARM (PVT) LTD.

About Rifaximin

Other Anti-infective Preps

Uses

Drug-resistant bacterial infection caused by rifaximin sensitive strains: Diarrhoea in patients (above 12 years age) caused by non-invasive strains of escherichia coli. For reduction in risk of overt hepatic encephalopathy recurrence in patients above 18 years of age.

How to take it

Diarrhoea: Adults: One 200 mg tablet three times a day for 3 days. Hepatic Encephalopathy: Adults: One 550 mg tablet two times a day, with or without food. Irritable bowel syndrome with diarrhoea (IBS-D): Adults: 550 mg three times a day for 14 days, may be given up to 2 times with the same dosing regimen if symptoms recur. Children: Not recommended.

Side effects

Bloating, gas, stomach pain; feeling like you need to empty your bowel urgently; nausea, vomiting, depression, dizziness, headache, dyspnoea, ascites, rash, muscle spasm, arthralgia, peripheral oedema, reddish discolouration of urine. Reports of Clostridium difficile infection.

Pregnancy and breastfeeding

Pregnancy: Contraindicated in pregnancy. Lactation: Caution advised or effect undetermined. Contraindications: Should not be used in patients with diarrhoea complicated by fever or blood in the stool or diarrhoea due to pathogens other than Escherichia coli. Precautions: Allergic to rifamycin. If patients develop difficulty in breathing, swelling of face, lip, tongue, or throat discontinue. Renal or severe hepatic impairment. Long term treatment (>6 months).

Advice

Take with or without meals. If a dose is missed, take it as soon as you remember unless it is almost time for the next dose. Discontinue medication and inform prescriber if diarrhoea remains for 2 or more days or if there is hives, difficulty in breathing, swelling on face, lips, tongue, or throat.

Full information on Rifaximin →

Interactions with Rifaximin

Anticoagulants, other rifamycins, combined oral contraceptives, CYP3A4 inhibitors or substrates, P-gp inhibitors.

Tell your pharmacist or doctor about every medicine you take, including herbal products.

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Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.