Nif-LA
by DeMont
Active ingredient: Nifedipine
Packs
- Tab · 60 mg · 20's
In stock at Healify — same active ingredient
Always confirm a substitution with your pharmacist.
About Nifedipine
Calcium Antagonist
Uses
Angina. Hypertension. Raynaud's phenomenon.
How to take it
Adults: Angina: Initially 10 mg three times daily adjusted according to response, usually 10-20 mg three times daily with or after meals. If immediate effect required, bite capsule and allow liquid to remain in the mouth. Hypertension: Initially 10-20 mg twice daily adjusting to response, usually 10-40 mg twice daily. Alternately 1 tab of 30 mg once daily, preferably in empty stomach; the dose, if necessary may be increased to 1 tab of 60 mg once daily. Raynaud's phenomenon: 10 mg three times daily with or after meals; max 20 mg three times daily. Children: Not recommended.
Side effects
Headache, flushes, oedema, dizziness, tachycardia, hypotension, GI upset, vasodilatation, lethargy, paraesthesia, skin reactions, myalgia, tremor, visual disturbances, increased urinary frequency, gingival hyperplasia, gynaecomastia. Rarely hypersensitivity type jaundice, impotence, mood changes. MI, ischaemic pain (discontinue).
Pregnancy and breastfeeding
Pregnancy: Contraindicated in pregnancy. Lactation: Contraindicated or not recommended. Contraindications: Cardiogenic shock, unstable angina, severe aortic stenosis, within a month of MI. Hepatic impairment, history of GI obstruction, Crohn's disease, Kock pouch, IBS, porphyria, malignant hypertension. Precautions: Poor cardiac reserve. Heart failure, hepatic impairment, severe hypotension, diabetes, dialysis. Elderly.
Advice
Take with non-fatty meals or without meals. Swallow whole, do not crush or chew sustained release forms. Do not take nifedipine within 1 hour of a high-fat meal or grapefruit. Do not stop taking medication abruptly, gradually decrease the dose, then stop. Contact prescriber if there is chest pain, palpitations, ringing in ears, rapid heartbeat, swelling of extremities, muscle weakness or pain, difficulty in breathing, nervousness, change in mood, rash or change in vision. Do not change the amount of grapefruit in diet without consulting prescriber. Taking low-fat, low-sodium meals, regular exercise, stress reduction, weight reduction are important lifestyle changes to be followed. Avoid…
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Interactions with Nifedipine
Antihypertensives, cimetidine, quinidine, digoxin, rifampicin, phenytoin, diltiazem, cisapride, erythromycin, azole antifungals, fluoxetine, indinavir, ritonavir, tacrolimus, quinupristin/dalfopristin, nefazodone, grapefruit juice, Beta blockers, carbamazepine, phenobarbital, valproic acid, macrolides, azole antifungals, protease inhibitors, mizolastine, fluoxetine, other inducers or inhibitors of CYP3A4, IV magnesium sulfate.
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Compiled by Healify Pharmacy from published drug references. How we compile it →
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