Nelvir

by A. J. Mirza

Active ingredient: Nelfinavir mesylate

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About Nelfinavir Mesylate

Antiviral, Systemic

Uses

HIV infection in combination with other antiretroviral drugs.

How to take it

Adults: 1.25 gm twice daily or 750 mg 3 times daily. Children: 3-13 yr, initially 50-55 mg/kg twice daily (max 1.25 gm twice daily) or 25-30 mg/kg 3 times daily (max 750 mg 3 times daily).

Side effects

Gastro-intestinal disturbances (including diarrhoea, nausea, vomiting, abdominal pain, flatulence), anorexia, hepatic dysfunction, pancreatitis; blood disorders including anaemia, neutropenia and thrombocytopenia, sleep disturbances, fatigue, headache, dizziness, paraesthesia, myalgia, myositis, rhabdomyolysis; taste disturbances; rash, pruritus, Stevens-Johnson syndrome, hypersensitivity reactions including anaphylaxis; lipodystrophy syndrome and osteonecrosis.

Pregnancy and breastfeeding

Pregnancy: No evidence of risk in humans. Lactation: Contraindicated or not recommended. Contraindications: Should not be given to patients with acute porphyria. Precautions: Patients with hyperglycaemia, patients with haemophilia, patients with hepatic impairment, patients with chronic hepatitis B or C.

Advice

Take with meals. Mix powder with non-acidic, non-citric fluids and reconstituted powder mixture should not be stored for more than 6 hours. If it is difficult for you to swallow whole tablet, dissolve it in water or add it in food and crush it. Take mixed or dissolved tablet within 6 hours. If you miss a dose, take it as soon as you remember unless it is time for the next dose. Do not take double dose. Contact prescriber if there is difficulty in breathing, rash, suicidal thoughts, confusion, migraine, weakness, muscle pain, skeletal pain, tremors. If therapy is for a long period of time, frequent blood tests are required.

Full information on Nelfinavir Mesylate →

Interactions with Nelfinavir Mesylate

See literature.

Tell your pharmacist or doctor about every medicine you take, including herbal products.

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More from A. J. Mirza

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.