Napzol
by Lowitt
Active ingredient: Esomeprazole
Packs
- Cap · 40 mg · 14's (052796)
- Cap · 20 mg · 14's (052796)
In stock at Healify — same active ingredient
Always confirm a substitution with your pharmacist.
About Esomeprazole
Antipeptic Ulcerant
Uses
Erosive reflux oesophagitis, prevention of relapse of oesophagitis, symptomatic treatment of GERD. Zollinger-Ellison syndrome, severe peptic ulcer bleeding (following endoscopic treatment). In combination with antibiotics for the eradication of H. pylori, healing of H. pylori-associated duodenal ulcer and prevention of relapse of H. pylori-associated peptic ulcers. Treatment and prevention of NSAID-associated peptic ulceration.
How to take it
ORAL: Adults: Erosive oesophagitis: 40 mg once daily for 4-8 wk. Prevention of relapse, 20 mg once daily. GERD without oesophagitis: 20 mg once daily for 4 wk. Maintenance, 20 mg once daily as required. Zollinger-Ellison syndrome: Initially 40 mg two times daily, can be altered according to response. Usual dose: 80-160 mg daily, doses over 80 mg must be given in two divided doses. Triple therapy vs H. pylori: 20 mg twice daily with amoxicillin 1 gm twice daily and clarithromycin 500 mg twice daily for 7 days. NSAID ulceration: 20 mg once daily for 4-8 wk, Prevention, 20 mg once daily. Children: Not recommended. INJECTION: Adults: Reflux oesophagitis: 40 mg once daily given as IV inj over a…
Side effects
Headache, GI upset, skin reaction, dry mouth. Rarely angioedema, anaphylaxis, fundic gland polyps.
Pregnancy and breastfeeding
Pregnancy: No evidence of risk in humans. Lactation: Contraindicated or not recommended. Precautions: Exclude malignant disease before and during treatment. Impaired renal or hepatic function, increased risk of GI infection. Monitor patients on long term therapy.
Advice
Take at least 1 hour before meals. Do not crush or chew, swallow whole. If there is difficulty in swallowing, open the capsule and mix all contents in a tablespoon of applesauce. Swallow immediately without chewing. Contact prescriber if there is constant headache, diarrhoea, constipation, stomach pain, changes in urination or pain on urination, chest pain or palpitations, alteration in respiratory status, CNS changes, constant muscular aches or pain, ringing in ears or visual changes.
Full information on Esomeprazole →
Interactions with Esomeprazole
Phenytoin, warfarin, clopidogrel, ketoconazole, itraconazole, voriconazole, protease inhibitors, diazepam, citalopram, imipramine, clomipramine, other CYP2C19 substrates, CYP3A4 inhibitors or inducers, tacrolimus, digoxin, erlotinib, methotrexate.
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Compiled by Healify Pharmacy from published drug references. How we compile it →
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