Methacid

by Unexo

Active ingredients: Indometacin, Indomethacin

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About Indomethacin

Anti-rheumatic, Systemic

Uses

Pain syndromes. Biliary & renal colics. Post-operative pain. Cancer pain. Chronic pain, rheumatoid arthritis, ankylosing spondylitis, osteoarthritis, musculoskeletal pain syndromes, acute gout and uretic rheumatism. Post-traumatic pain. Sport injuries.

How to take it

ORAL: Adults & Children: > 14 yr: Rheumatoid Arthritis/Osteoarthritis: Initial: 25 mg every 8 or 12 hr. Titrate: increase by 25-50 mg/day weekly. Max: 200 mg/day. Bursitis/Tendinitis: 75-150 mg/day given every 8 or 12 hr for 7-14 days. Acute Gouty Arthritis: 50 mg 3 times daily. SUPPOSITORY: Adults: 100-200 mg daily or 100 mg at night. Total 200 mg daily. Children: Not recommended.

Side effects

Gastro-intestinal bleeding, persistent headache (discontinue if occur). Corneal deposits, retinal disturbances (perform periodic eye tests on long term use), melaena, haematemesis, dizziness, CNS effects, blood dyscrasias.

Pregnancy and breastfeeding

Pregnancy: Contraindicated in pregnancy. Lactation: Contraindicated or not recommended. Contraindications: Active peptic ulcer, history of GIT lesions, aspirin or anti-inflammatory induced allergy. Severe cardiac, hepatic or renal failure. Nasal polyps. Precautions: Renal or hepatic impairment, monitor on long term therapy. Mild to moderate heart failure, hypertension, ischaemic heart, peripheral arterial or cerebrovascular disease, cardiac risk factors, diabetes, volume depletion. History of GI disease. SLE, mixed connective tissue disorders, epilepsy, bleeding disorders, psychiatric disorders, parkinsonism, infection, surgery. Asthma. Monitor haematological, hepatic and GI effects. Use…

Advice

Take with meals. Do not crush, break or chew capsules. Swallow whole with a glass of water. Do not lie down for 15-30 minutes after taking medication. Discontinue medication and inform prescriber if there is constant abdominal pain, cramps, indigestion, blood in stool. Contact prescriber if there is chest pain, palpitations, fast heartbeat, difficulty in breathing, unusual cough, unusual bruising or bleeding, blood in urine/gums/vomitus, acute fatigue, skin rash, itching, irritation, blisters, swelling in ankles/hands/feet, change in vision, change in hearing, ringing in ears, difficulty in speaking. Avoid alcohol during therapy. Take sufficient amount of fluids (2-3 litres per day) to…

Full information on Indomethacin →

Interactions with Indomethacin

Salicylates, anticoagulants, lithium, corticosteroids, diuretics, beta-blockers, probenecid, quinolones, other NSAIDs, antiplatelets, cyclosporin, methotrexate, digoxin, antihypertensives, nephrotoxic drugs, SSRIs, live vaccines, antidiabetics, mifepristone, baclofen, triamterene, vasodilators, tacrolimus, phenytoin, haloperidol, cyclophosphamide, desmopressin.

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Compiled by Healify Pharmacy from published drug references. How we compile it →

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