Letsbe
by Davis
Active ingredient: Letrozole
Packs
- Tab · 2.5 mg · 30's
In stock at Healify — same active ingredient
Always confirm a substitution with your pharmacist.
About Letrozole
Cytostatic
Uses
Advanced post-menopausal breast-cancer resistant to tamoxifen or other anti-oestrogens.
How to take it
Adults: 1 tab daily. Children: Not applicable.
Side effects
Musculoskeletal pain, headache, GI upset, dyspnoea, cough, chest pain, viral infections, hot flushes, abdominal pain, fatigue, hypercholesterolaemia, sweating, appetite changes, depression, dizziness, palpitations, hypertension, alopecia, rash, dry skin, arthralgia, myalgia, bone pain, osteoporosis, arthritis, vaginal bleeding, peripheral oedema, wt changes. Reports of cardiovascular events.
Pregnancy and breastfeeding
Pregnancy: Positive evidence of risk: Use only when no safer alternative exists for a serious problem. Lactation: Contraindicated or not recommended. Contraindications: Pre-menopausal women, very severe hepatic impairment, pre-op use if receptor status negative or unknown. Precautions: Monitor bone mineral density during adjuvant therapy in women with or at risk of osteoporosis. Very severe renal impairment, severe hepatic impairment.
Advice
Take with or without meals. Consult prescriber for mild analgesic if you have musculoskeletal pain or headache. Contact prescriber if there is skin rash, severe nausea, muscle pain, difficulty in breathing, chest pain, palpitations, swelling of extremities, weakness, numbness, severe headache, difficulty in speaking, unusual signs of bruising or bleeding, vaginal bleeding, difficulty in breathing.
Full information on Letrozole →
Interactions with Letrozole
Tamoxifen, oestrogens. Substrates of CYP2A6 or CYP2C19 that have a narrow therapeutic index.
Tell your pharmacist or doctor about every medicine you take, including herbal products.
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Compiled by Healify Pharmacy from published drug references. How we compile it →
Always consult a pharmacist or doctor.