Kenzol

by Reko

Active ingredient: Ketoconazole

Packs

About Ketoconazole, Oral

Antifungal, Systemic

Uses

Systemic mycoses, prophylaxis of mycoses in patients with reduced immune responses. Serious chronic mucocutaneous candidiasis and serious mycoses of the Gl tract not responsive to other therapy. Culturally determined dermatophyte infections not responsive to other therapy excluding infection of the toe nails or for pityriasis versicolor.

How to take it

Adults: 200-400 mg once daily with meals. May increase to 400 mg daily. Continue for at least one wk after symptoms have cleared. Children: >2 yr, 3.3-6.6 mg/kg, once daily with meals; for candidiasis 1-2 wk; for 4 wk in recalcitrant, dermatophyte infections; up to 6 mth for other systemic mycoses.

Side effects

Altered liver function tests and hepatitis. Hypersensitivity reactions. Gl upsets, rashes, headache, thrombocytopenia. Gynaecomastia (rare).

Pregnancy and breastfeeding

Pregnancy: Contraindicated in pregnancy. Lactation: Contraindicated or not recommended. Contraindications: Pre-existing liver disease or significant abnormalities on liver function tests. Precautions: Monitor patients for signs of liver damage after first 10 days, then twice per month.

Advice

Take with meals. Do not take within 2 hours of taking an antacid. Contact prescriber if there is unrelieved headache, itching, rash, yellowing of skin or eyes, colour change of stool or urine, chest pain, palpitations, ringing in ears, feeling of fullness. Complete full course of therapy even if you feel better. If you have diabetes, monitor blood glucose regularly and inform prescriber about the changes. Mild analgesic may be taken for headache.

Full information on Ketoconazole, Oral →

Interactions with Ketoconazole, Oral

Anticholinergics, antacids, H2-antagonists, anticoagulants, phenytoin, rifampicin, cyclosporin A.

Tell your pharmacist or doctor about every medicine you take, including herbal products.

Need Kenzol? Ask us to source Kenzol and our pharmacist will call you back.

Other brands with the same ingredients

More from Reko

Compiled by Healify Pharmacy from published drug references. How we compile it →

Always consult a pharmacist or doctor.