Kadex

by Nova Med

Active ingredient: Ketorolac

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About Ketorolac Tromethamine

Non-narcotic Analgesic

Uses

Short-term management of moderate to severe post- operative pain.

How to take it

Adults: 16 yr to <65 yr: Single Dose: 60 mg IM or 30 mg IV. Multiple Dose: 30 mg IV/IM every 6 hr. Max: 120 mg/day for 2 days. >65 yr or <50 kg: Single Dose: 30 mg IM or 15 mg IV. Multiple Dose: 15 mg IV/IM every 6 hr. Max: 60 mg/day for 2 days. Children: Under 16 yr, not recommended. Tab: 20 mg once after IV/IM therapy, then 10 mg q4-6 hr; not to exceed 40 mg/day. IM: Administer slowly and deeply into the muscle. Analgesia begins in 30 min & max effect within 2 hours. IV: Administer IV bolus over a minimum of 15 seconds; onset within 30 min; peak analgesia within 2 hours. Compatibility: Stable in D5NS, D5W, LR, NS. Y-site administration: Drug to Drug IV Compatibility: Cisatracurium,…

Side effects

GI disturbances, ulcers, bleeds. Wound haemorrhage. Abnormal liver function tests. Drowsiness, acute renal failure, oedema, bronchospasm, anaphylaxis, pain at injection site, thrombocytopenia, hepatitis, liver failure. CNS, respiratory or cardiovascular disorders, thirst, asthenia, myalgia, fever, chest pain, elevated serum creatinine and urea, electrolyte disturbances, hypersensitivity and skin reactions.

Pregnancy and breastfeeding

Pregnancy: Risk cannot be ruled out. Lactation: Contraindicated or not recommended. Contraindications: Peptic ulcer, GI or cerebrovascular bleeding, haemorrhagic diathesis, aspirin/anti-inflammatory induced allergies, coagulation disorders, asthma, hepatic or renal impairment, hypovolaemia, dehydration, severe heart failure, nasal polyps, angioedema. High risk of surgically-induced haemorrhage. Precautions: Elderly, GI disease, cardiac, renal, hepatic or allergic disease. Haemostasis. Mild to moderate heart failure, ischaemic heart disease, cerebrovascular disease, peripheral arterial disease. Hypertension, other cardiovascular risk factors. SLE, mixed connective tissue disorders. Use…

Advice

Take oral form with meals. Take medication with a full glass of water and stay upright for atleast 15 minutes after taking medication. Discontinue medication and report immediately abdominal pain, blood in urine or stool. Contact prescriber if there is unrelieved nausea or vomiting, difficulty in breathing, difficulty in speaking, ringing in ears, ulceration, skin rash, itching, easy bruising or bleeding, chest pain, palpitations, unusual swelling of extremities, yellowing of eyes or skin. Avoid alcohol during therapy. Take sufficient amount of fluids (2-3 litres per day) to maintain hydration, unless restricted by the prescriber. Maintain good oral hygiene and use a soft-bristled…

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Interactions with Ketorolac Tromethamine

Anticoagulants, lithium, NSAIDs, methotrexate, probenecid, aspirin, diuretics, pentoxifylline, antihypertensives, SSRIs, corticosteroids, mifepristone, cyclosporin, tacrolimus, digoxin, quinolones, zidovudine.

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Compiled by Healify Pharmacy from published drug references. How we compile it →

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