Gravibinan

by Bayer

Active ingredients: Estradiol valerate, Hydroxyprogesterone caproate, Oestrogen

PKR 415

Available at Healify

Gravibinan 1ml · Injection · PKR 415 · In stock · Prescription medicine
Gravibinan 2ml · Injection · PKR 727 · In stock · Prescription medicine

Other packs (not sold online by Healify)

Inj · 1 Amp (1 mL) (000798)
Inj · 1 Amp (2 mL) (000798)

About Estradiol Valerate

Oestrogen, their Combinations & related Preps

Uses

HRT for climacteric syndrome. Prophylaxis of osteoporosis.

How to take it

Adults: Climacteric syndrome: 1 mg or 2 mg daily. For maintenance, use lowest effective dose. Prophylaxis of osteoporosis: 2 mg daily. In women with an intact uterus add a progestogen for 12 days of each cycle. Children: Not applicable.

Side effects

Nausea, vomiting, weight gain, breast tenderness & enlargement, withdrawal bleeding, sodium retention with oedema, liver function disorders, jaundice, rashes, chloasma, headache. Endometrial carcinoma in post-menopausal women.

Pregnancy and breastfeeding

Contraindications: History of, or predisposition to, thrombophlebitis, thromboembolic disorders, cerebrovascular disease. History of pruritus, during pregnancy deteriorating otosclerosis, idiopathic jaundice or pemphigus gestations (herpes gestations). Impaired hepatic excretory function such as Dubin-Johnson & Rotor syndromes. Sickle cell anaemia. Acute or chronic liver disease, jaundice, porphyria, disorders of lipid metabolism. Oestrogen dependent carcinomas, endometriosis, undiagnosed genital bleeding. Pregnancy. Lactation. Precautions: Hypertension, myocardial or renal disease, asthma, varicose veins, epilepsy, chloasma, uterine fibromyomata. Examine BP, pelvic organs & breasts before…

Full information on Estradiol Valerate →

Interactions with Estradiol Valerate

Diuretics, antihypertensives, liver enzyme inducing drugs.

Tell your pharmacist or doctor about every medicine you take, including herbal products.