Glyrol
by Medisure
Active ingredient: Pioglitazone
Packs
- Tab · 15 mg · 14's (032806)
- Tab · 30 mg · 14's (032807)
- Tab · 45 mg · 14's (032808)
In stock at Healify — same active ingredient
Always confirm a substitution with your pharmacist.
About Pioglitazone
Hypoglycaemic excluding Insulin
Uses
Monotherapy for type II diabetes, particularly overweight patients, inadequately controlled by diet and exercise for whom metformin is inappropriate. In combination with metformin particularly in overweight patients, or in combination with a sulphonylurea in patients with an intolerance or contraindication to metformin, for type II diabetes inadequately controlled by maximal tolerated doses of either metformin or a sulphonylureas.
How to take it
Monotherapy: Adults: 15-30 mg once daily, increasing to 45 mg once daily if necessary. Combination therapy: Adults: 15-30 mg once daily, increasing to 45 mg once daily if necessary, in combination with current dose of metformin or sulphonylureas. Children: Not recommended.
Side effects
Monotherapy: Visual disturbance, upper respiratory tract infection, weight gain, hypoesthesia. With metformin: Anaemia, weight gain, headache, visual disturbance, arthralgia, haematuria, erectile dysfunction, oedema. With a sulphonylureas: Weight gain, dizziness, flatulence, oedema, arthralgia. Triple therapy: Raised creatine kinase, hypoglycaemia, arthralgia. With insulin: Hypoglycaemia, back pain, arthralgia, dyspnoea, cardiac failure.
Pregnancy and breastfeeding
Pregnancy: Risk cannot be ruled out. Lactation: Contraindicated or not recommended. Contraindications: Dialysis, hepatic impairment. Cardiac failure or history of cardiac failure, diabetic ketoacidosis. Bladder cancer or history of bladder cancer, uninvestigated haematuria. Precautions: Monitor for fluid retention or other signs of cardiac failure (discontinue if deteriorates). Monitor for signs of hepatic dysfunction and check liver enzymes prior to therapy and every 2 months thereafter for at least 12 months. Monitor body weight.
Advice
Take with or without meals. If a dose is missed, take as soon as possible. Do not double the dose next day if a dose is missed completely one day. Contact prescriber if there is respiratory infection; unusual weight gain; worsening of hyper/hypo glycaemic condition; unusual swelling of extremities; shortness of breath; fatigue; yellowing of skin or eyes; dark urine; pale stool, nausea, vomiting or muscle pain. Follow prescribed dietary and lifestyle recommendations. Follow glucose monitoring instructions as prescribed. Keep appointments for liver function tests, as prescribed, typically every 2 months during first year of therapy and annually thereafter. Female patients are at risk for…
Full information on Pioglitazone →
Interactions with Pioglitazone
Insulin (contraindicated), NSAIDs, gemfibrozil, rifampicin.
Tell your pharmacist or doctor about every medicine you take, including herbal products.
Need Glyrol? Ask us to source Glyrol and our pharmacist will call you back.
Other brands with the same ingredients
More from Medisure
Compiled by Healify Pharmacy from published drug references. How we compile it →
Always consult a pharmacist or doctor.